PMID- 16339850
OWN - NLM
STAT- MEDLINE
DCOM- 20060417
LR  - 20220408
IS  - 1040-4651 (Print)
IS  - 1532-298X (Electronic)
IS  - 1040-4651 (Linking)
VI  - 18
IP  - 1
DP  - 2006 Jan
TI  - Arabidopsis CONSTANS-LIKE3 is a positive regulator of red light signaling and 
      root growth.
PG  - 70-84
AB  - CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1) is an E3 ubiquitin ligase that represses 
      photomorphogenesis in the dark. Therefore, proteins interacting with COP1 could 
      be important regulators of light-dependent development. Here, we identify 
      CONSTANS-LIKE3 (COL3) as a novel interaction partner of COP1. A green fluorescent 
      protein-COL3 fusion protein colocalizes with COP1 to nuclear speckles when 
      transiently expressed in plant cells. This localization requires the B-box 
      domains in COL3, indicating a novel function of this domain. A loss-of-function 
      col3 mutant has longer hypocotyls in red light and in short days. Unlike 
      constans, the col3 mutant flowers early and shows a reduced number of lateral 
      branches in short days. The mutant also exhibits reduced formation of lateral 
      roots. The col3 mutation partially suppresses the cop1 and deetiolated1 (det1) 
      mutations in the dark, suggesting that COL3 acts downstream of both of these 
      repressors. However, the col3 mutation exerts opposing effects on cop1 and det1 
      in terms of lateral roots and anthocyanin accumulation, suggesting that COL3 also 
      has activities that are independent of COP1 and DET1. In conclusion, we have 
      identified COL3 as a positive regulator of photomorphogenesis that acts 
      downstream of COP1 but can promote lateral root development independently of COP1 
      and also function as a daylength-sensitive regulator of shoot branching.
FAU - Datta, Sourav
AU  - Datta S
AD  - Department of Cell and Molecular Biology, Gothenburg University, Sweden.
FAU - Hettiarachchi, G H C M
AU  - Hettiarachchi GH
FAU - Deng, Xing-Wang
AU  - Deng XW
FAU - Holm, Magnus
AU  - Holm M
LA  - eng
GR  - R01 GM047850/GM/NIGMS NIH HHS/United States
GR  - R37 GM047850/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20051209
PL  - England
TA  - Plant Cell
JT  - The Plant cell
JID - 9208688
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (COL3 protein, Arabidopsis)
RN  - 0 (CONSTANS protein, Arabidopsis)
RN  - 0 (Carrier Proteins)
RN  - 0 (DET1 protein, Arabidopsis)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (Intracellular Signaling Peptides and Proteins)
RN  - 0 (Nuclear Proteins)
RN  - 0 (Protein Isoforms)
RN  - 0 (Recombinant Fusion Proteins)
RN  - 0 (Transcription Factors)
RN  - EC 2.3.2.27 (AT2G32950 protein, Arabidopsis)
RN  - EC 2.3.2.27 (Ubiquitin-Protein Ligases)
SB  - IM
MH  - Amino Acid Sequence
MH  - Arabidopsis/*anatomy & histology/genetics/*physiology
MH  - Arabidopsis Proteins/genetics/*metabolism
MH  - Carrier Proteins/genetics/*metabolism
MH  - Cell Nucleus/metabolism
MH  - DNA-Binding Proteins/genetics/*metabolism
MH  - Flowers/anatomy & histology/physiology
MH  - Gene Expression Regulation, Plant
MH  - Hypocotyl/anatomy & histology/metabolism
MH  - Intracellular Signaling Peptides and Proteins
MH  - *Light
MH  - Molecular Sequence Data
MH  - Morphogenesis/physiology
MH  - Nuclear Proteins/genetics/metabolism
MH  - Photoperiod
MH  - Plant Roots/anatomy & histology/*growth & development
MH  - Protein Isoforms/genetics/*metabolism
MH  - Protein Structure, Tertiary
MH  - Recombinant Fusion Proteins/genetics/metabolism
MH  - Sequence Alignment
MH  - Signal Transduction/*physiology
MH  - Transcription Factors/genetics/*metabolism
MH  - Two-Hybrid System Techniques
MH  - Ubiquitin-Protein Ligases/genetics/metabolism
PMC - PMC1323485
EDAT- 2005/12/13 09:00
MHDA- 2006/04/18 09:00
CRDT- 2005/12/13 09:00
PHST- 2005/12/13 09:00 [pubmed]
PHST- 2006/04/18 09:00 [medline]
PHST- 2005/12/13 09:00 [entrez]
AID - tpc.105.038182 [pii]
AID - 038182 [pii]
AID - 10.1105/tpc.105.038182 [doi]
PST - ppublish
SO  - Plant Cell. 2006 Jan;18(1):70-84. doi: 10.1105/tpc.105.038182. Epub 2005 Dec 9.