PMID- 16352486
OWN - NLM
STAT- MEDLINE
DCOM- 20060321
LR  - 20081121
IS  - 1401-7431 (Print)
IS  - 1401-7431 (Linking)
VI  - 39
IP  - 6
DP  - 2005 Dec
TI  - Epicardial and endocardial dispersion of ventricular repolarization. A study of 
      monophasic action potential mapping in healthy pigs.
PG  - 342-7
AB  - OBJECTIVES: To investigate the total dispersion of ventricular repolarization of 
      the epi- and endocardium. DESIGN: Monophasic action potentials (MAP) were 
      recorded from 211+/-54 (151-353) left and right ventricular epi- and endocardial 
      sites during atrial pacing in 10 pigs using the CARTO system. The activation time 
      (AT), MAP duration (MAPd) and end of repolarization time (EOR) were measured. 
      RESULTS: The total dispersion of AT, EOR and MAPd, defined as the maximal 
      differences of these parameters over both the epi- and endocardium, were 57+/-10, 
      84+/-20, and 75+/-21 ms respectively and were significantly larger than the 
      respective epi- and endocardial dispersions (p<0.05). The epicardial dispersion 
      of AT, EOR and MAPd of both the right and left ventricles were significantly 
      larger than that of each ventricle alone (p<0.02). Sternotomy did not affect 
      these dispersion parameters. CONCLUSION: Detailed mapping of epicardial 
      repolarization in vivo using the MAP mapping technique is feasible. Both the epi- 
      and endocardium of the two ventricles contribute significantly to the total 
      dispersion of repolarization.
FAU - Kongstad, Ole
AU  - Kongstad O
AD  - Department of Cardiology, University Hospital, Lund, Sweden. 
      Ole.kongstad@skane.se
FAU - Xia, Yunlong
AU  - Xia Y
FAU - Liang, Yanchun
AU  - Liang Y
FAU - Hertervig, Eva
AU  - Hertervig E
FAU - Ljungstrom, Erik
AU  - Ljungstrom E
FAU - Olsson, Bertil
AU  - Olsson B
FAU - Yuan, Shiwen
AU  - Yuan S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Scand Cardiovasc J
JT  - Scandinavian cardiovascular journal : SCJ
JID - 9708377
SB  - IM
MH  - *Action Potentials
MH  - Animals
MH  - *Body Surface Potential Mapping
MH  - *Cardiac Pacing, Artificial
MH  - Endocardium/*physiology
MH  - Heart Conduction System/*physiology
MH  - Pericardium/*physiology
MH  - Swine
MH  - Time Factors
MH  - *Ventricular Function
EDAT- 2005/12/15 09:00
MHDA- 2006/03/22 09:00
CRDT- 2005/12/15 09:00
PHST- 2005/12/15 09:00 [pubmed]
PHST- 2006/03/22 09:00 [medline]
PHST- 2005/12/15 09:00 [entrez]
AID - RH03616072N17711 [pii]
AID - 10.1080/14017430500188744 [doi]
PST - ppublish
SO  - Scand Cardiovasc J. 2005 Dec;39(6):342-7. doi: 10.1080/14017430500188744.