PMID- 16353687
OWN - NLM
STAT- MEDLINE
DCOM- 20060120
LR  - 20131121
IS  - 1661-8157 (Print)
IS  - 1661-8157 (Linking)
VI  - 94
IP  - 48
DP  - 2005 Nov 30
TI  - [Gastroesophageal reflux disease].
PG  - 1899-906
AB  - Gastroesophageal reflux disease (GERD) includes different manifestations of 
      esophageal and extraesophageal affections, such as erosive reflux disease, 
      Barrett's esophagus, laryngitis and even pulmonary diseases. Typical symptoms are 
      heartburn and acid regurgitation, but there are a lot of atypical disturbances 
      like hoarseness or chronic cough. Endoscopy is the most important diagnostic 
      procedure for elderly patients and for those with atypical symptoms. Younger 
      people without alarming symptoms can be tested for GERD by treatment with proton 
      pump inhibitors (PPI). The therapeutic approach depends on the endoscopic 
      findings. PPI are preferred drugs to manage most GERD-related problems. Anti 
      reflux surgery is appropriate for selected patients. Long-term followup data will 
      help to define the benefit of new endoscopic procedures. Barrett's esophagus has 
      to be regarded as a precancerous lesion, therefore surveillance strategy is 
      required.
FAU - Grater, H
AU  - Grater H
AD  - Klinik fur Onkologie, Gastroenterologie und Aligemeine Innere Medizin, Stadtische 
      Kliniken Esslingen.
LA  - ger
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Gastroosophageale Refluxkrankheit.
PL  - Switzerland
TA  - Praxis (Bern 1994)
JT  - Praxis
JID - 101468093
RN  - 0 (Antacids)
RN  - 0 (Anti-Ulcer Agents)
RN  - 0 (Proton Pump Inhibitors)
RN  - UVL329170W (Cisapride)
SB  - IM
MH  - Aged
MH  - Antacids/therapeutic use
MH  - Anti-Ulcer Agents/therapeutic use
MH  - Barrett Esophagus/diagnosis/drug therapy/physiopathology
MH  - Biopsy
MH  - Cisapride/therapeutic use
MH  - Diagnosis, Differential
MH  - Endoscopy
MH  - Endoscopy, Digestive System
MH  - Esophagus/pathology
MH  - Follow-Up Studies
MH  - *Gastroesophageal Reflux/diagnosis/drug therapy/pathology/physiopathology/surgery
MH  - Humans
MH  - Patient Selection
MH  - Proton Pump Inhibitors
MH  - Time Factors
RF  - 29
EDAT- 2005/12/16 09:00
MHDA- 2006/01/21 09:00
CRDT- 2005/12/16 09:00
PHST- 2005/12/16 09:00 [pubmed]
PHST- 2006/01/21 09:00 [medline]
PHST- 2005/12/16 09:00 [entrez]
AID - 10.1024/0369-8394.94.48.1899 [doi]
PST - ppublish
SO  - Praxis (Bern 1994). 2005 Nov 30;94(48):1899-906. doi: 
      10.1024/0369-8394.94.48.1899.