PMID- 16353787
OWN - NLM
STAT- MEDLINE
DCOM- 20060321
LR  - 20191109
IS  - 0001-6519 (Print)
IS  - 0001-6519 (Linking)
VI  - 56
IP  - 9
DP  - 2005 Nov
TI  - [Gastroesophageal reflux and obstructive sleep apnea syndrome].
PG  - 411-5
AB  - INTRODUCTION: Patients with mild or moderate Sleep Apnea Syndrome (SAS) need 
      wider therapeutic scope options according to their disease severity. AIM: To 
      consider including proton pump inhibitors (PPI) to the therapeutical alternatives 
      of these patients. MATERIAL AND METHODS: A prospective study was designed, among 
      patients with SAS. Nocturnal polysomnography and double channel pHmetry were 
      performed simultaneously. RESULTS: From the 18 patients included in this 
      preliminary phase, in three (16.7%) nocturnal proximal ph monitoring was 
      positive. These 3 patients were treated with PPI during at least 3 months with a 
      very satisfactory outcome in two of them. CONCLUSIONS: Treatment with PPI may be 
      a useful therapeutical alternative in patients with mild to moderate SAS.
FAU - Esteller, E
AU  - Esteller E
AD  - Servicio de Otorrinolaringologia, Hospital General de Catalunya, San Cugat del 
      Valles, Barcelona. esteller@abaforum.es
FAU - Modolell, I
AU  - Modolell I
FAU - Segarra, F
AU  - Segarra F
FAU - Matino, E
AU  - Matino E
FAU - Enrique, A
AU  - Enrique A
FAU - Adema, J M
AU  - Adema JM
FAU - Estivill, E
AU  - Estivill E
LA  - spa
PT  - Journal Article
TT  - Reflujo gastroesofagico proximal y sindrome de la apnea obstructiva del sueno. 
      Datos preliminares de un estudio prospectivo.
PL  - Spain
TA  - Acta Otorrinolaringol Esp
JT  - Acta otorrinolaringologica espanola
JID - 14540260R
RN  - 0 (2-Pyridinylmethylsulfinylbenzimidazoles)
RN  - 0 (Benzimidazoles)
RN  - 0 (Proton Pump Inhibitors)
RN  - 0 (Sulfoxides)
RN  - D8TST4O562 (Pantoprazole)
RN  - KG60484QX9 (Omeprazole)
SB  - IM
MH  - 2-Pyridinylmethylsulfinylbenzimidazoles
MH  - Adult
MH  - Benzimidazoles/*therapeutic use
MH  - Female
MH  - Gastroesophageal Reflux/*complications/*drug therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Omeprazole/*analogs & derivatives/therapeutic use
MH  - Pantoprazole
MH  - Prospective Studies
MH  - *Proton Pump Inhibitors
MH  - Sleep Apnea, Obstructive/*complications
MH  - Sulfoxides/*therapeutic use
EDAT- 2005/12/16 09:00
MHDA- 2006/03/22 09:00
CRDT- 2005/12/16 09:00
PHST- 2005/12/16 09:00 [pubmed]
PHST- 2006/03/22 09:00 [medline]
PHST- 2005/12/16 09:00 [entrez]
AID - 10.1016/s0001-6519(05)78639-8 [doi]
PST - ppublish
SO  - Acta Otorrinolaringol Esp. 2005 Nov;56(9):411-5. doi: 
      10.1016/s0001-6519(05)78639-8.