PMID- 16362893 OWN - NLM STAT- MEDLINE DCOM- 20060321 LR - 20200403 IS - 0022-1899 (Print) IS - 1537-6613 (Electronic) IS - 0022-1899 (Linking) VI - 193 IP - 2 DP - 2006 Jan 15 TI - Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan. PG - 283-6 AB - We investigated whether infection with a novel human coronavirus (HCoV), called "New Haven coronavirus" (HCoV-NH)--which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63--is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoV-NL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan. FAU - Chang, Luan-Yin AU - Chang LY AD - Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan. FAU - Chiang, Bor-Luen AU - Chiang BL FAU - Kao, Chuan-Liang AU - Kao CL FAU - Wu, Mei-Hwan AU - Wu MH FAU - Chen, Pei-Jer AU - Chen PJ FAU - Berkhout, Ben AU - Berkhout B FAU - Yang, Hui-Ching AU - Yang HC FAU - Huang, Li-Min AU - Huang LM CN - Kawasaki Disease Research Group LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20051202 PL - United States TA - J Infect Dis JT - The Journal of infectious diseases JID - 0413675 RN - 0 (RNA, Viral) SB - IM MH - Child, Preschool MH - Coronavirus/genetics/*isolation & purification MH - Coronavirus Infections/*complications MH - Female MH - Humans MH - Infant MH - Leukocytes, Mononuclear/virology MH - Male MH - Mucocutaneous Lymph Node Syndrome/*etiology/virology MH - Nasopharynx/virology MH - Pharynx/virology MH - RNA, Viral/analysis MH - Rectum/virology MH - Reverse Transcriptase Polymerase Chain Reaction MH - Serum/virology MH - Taiwan PMC - PMC7109937 COIS- Potential conflicts of interest: none reported EDAT- 2005/12/20 09:00 MHDA- 2006/03/22 09:00 PMCR- 2006/01/15 CRDT- 2005/12/20 09:00 PHST- 2005/06/01 00:00 [received] PHST- 2005/08/09 00:00 [accepted] PHST- 2005/12/20 09:00 [pubmed] PHST- 2006/03/22 09:00 [medline] PHST- 2005/12/20 09:00 [entrez] PHST- 2006/01/15 00:00 [pmc-release] AID - JID35037 [pii] AID - 10.1086/498875 [doi] PST - ppublish SO - J Infect Dis. 2006 Jan 15;193(2):283-6. doi: 10.1086/498875. Epub 2005 Dec 2.