PMID- 16365721 OWN - NLM STAT- MEDLINE DCOM- 20060525 LR - 20220316 IS - 1432-6981 (Print) IS - 1432-6981 (Linking) VI - 10 IP - 1 DP - 2006 Mar TI - Healing of intrabony defects following treatment with an oily calcium hydroxide suspension (Osteoinductal). A controlled clinical study. PG - 55-60 AB - The purpose of the present clinical study was to evaluate the healing of deep intrabony defects following the application of an oily calcium hydroxide suspension (OCHS). Thirty patients suffering from chronic periodontitis, each of whom displayed one intrabony defect, were randomly treated with access flap surgery (AFS) and the application of OCHS (test) or with AFS alone (control). The following clinical parameters were recorded at baseline and at 6 months after therapy: plaque index, gingival index, bleeding on probing, probing depth (PD), gingival recession, and clinical attachment level (CAL). No differences in any of the investigated parameters were observed at baseline between the two groups. At 6 months after therapy, the test group showed a reduction in mean PD from 7.7+/-1.5 to 2.9+/-0.9 mm (P<0.001) and a change in mean CAL from 9.6+/-2.1 to 5.5+/-2.5 mm (P<0.001). In the control group, the mean PD was reduced from 6.9+/-0.9 to 3.7+/-0.9 mm (P<0.001) and the mean CAL changed from 8.5+/-2.5 to 6.4+/-2.7 mm (P<0.001). OCHS resulted in statistically significant higher PD reductions (P<0.01) and CAL gains (P<0.05) than AFS alone. Within the limits of the present study, it can be concluded that: (1) at 6 months after surgery both therapies resulted in statistically significant PD reductions and CAL gains and (2) treatment with OCHS resulted in statistically significant higher CAL gains than treatment with AFS alone. FAU - Stratul, Stefan-Ioan AU - Stratul SI AD - Department of Periodontology, Victor-Babes University of Medicine, Timisoara, Romania. FAU - Schwarz, Frank AU - Schwarz F FAU - Becker, Jurgen AU - Becker J FAU - Willershausen, Britta AU - Willershausen B FAU - Sculean, Anton AU - Sculean A LA - eng PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial DEP - 20051220 PL - Germany TA - Clin Oral Investig JT - Clinical oral investigations JID - 9707115 RN - 0 (Bone Substitutes) RN - 0 (Osteoinductal) RN - PF5DZW74VN (Calcium Hydroxide) MH - Adult MH - Alveolar Bone Loss/*surgery MH - Bone Substitutes/*therapeutic use MH - Calcium Hydroxide/*therapeutic use MH - Chronic Disease MH - Dental Plaque Index MH - Female MH - Follow-Up Studies MH - Gingival Hemorrhage/surgery MH - Gingival Recession/surgery MH - Humans MH - Male MH - Periodontal Attachment Loss/surgery MH - Periodontal Index MH - Periodontal Pocket/surgery MH - Periodontitis/*surgery MH - Surgical Flaps MH - Wound Healing/drug effects EDAT- 2005/12/21 09:00 MHDA- 2006/05/26 09:00 CRDT- 2005/12/21 09:00 PHST- 2005/07/21 00:00 [received] PHST- 2005/11/25 00:00 [accepted] PHST- 2005/12/21 09:00 [pubmed] PHST- 2006/05/26 09:00 [medline] PHST- 2005/12/21 09:00 [entrez] AID - 10.1007/s00784-005-0024-1 [doi] PST - ppublish SO - Clin Oral Investig. 2006 Mar;10(1):55-60. doi: 10.1007/s00784-005-0024-1. Epub 2005 Dec 20.