PMID- 1636617
OWN - NLM
STAT- MEDLINE
DCOM- 19920825
LR  - 20180330
IS  - 0002-9165 (Print)
IS  - 0002-9165 (Linking)
VI  - 56
IP  - 2
DP  - 1992 Aug
TI  - Effects of diets rich in monounsaturated fatty acids on plasma lipoproteins--the 
      Jerusalem Nutrition Study. II. Monounsaturated fatty acids vs carbohydrates.
PG  - 394-403
AB  - Seventeen male Yeshiva students were randomly allocated to a crossover study with 
      two 12-wk dietary periods of monounsaturated fatty acids (MUFAs) vs a 
      carbohydrate (CHO)-rich diet while concentrations of saturated (SFAs) and 
      polyunsaturated (PUFAs) fatty acids were kept similar. Total plasma cholesterol 
      (TC) decreased significantly by approximately 7.7% and low-density-lipoprotein 
      cholesterol (LDL-C) by 14.4% on the MUFA diet, whereas on the CHO diet no 
      significant change in cholesterol concentrations occurred, in contrast to that 
      predicted by the equations of Keys and Hegsted. Concentrations of 
      high-density-lipoprotein cholesterol (HDL-C) did not change significantly on 
      either diet. On the MUFA diet there was a significantly lower proneness to 
      peroxidation of plasma and LDL lipids and less extensive metabolism of 
      conditioned LDL by peritoneal macrophages. We conclude that dietary MUFAs lower 
      TC and LDL-C concentrations, independently of other dietary fatty acids and in 
      addition may reduce the susceptibility of LDL to oxidative stress.
FAU - Berry, E M
AU  - Berry EM
AD  - Department of Medicine, Hadassah University Hospital, Jerusalem, Israel.
FAU - Eisenberg, S
AU  - Eisenberg S
FAU - Friedlander, Y
AU  - Friedlander Y
FAU - Harats, D
AU  - Harats D
FAU - Kaufmann, N A
AU  - Kaufmann NA
FAU - Norman, Y
AU  - Norman Y
FAU - Stein, Y
AU  - Stein Y
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Am J Clin Nutr
JT  - The American journal of clinical nutrition
JID - 0376027
RN  - 0 (Cholesterol, HDL)
RN  - 0 (Cholesterol, LDL)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats, Unsaturated)
RN  - 0 (Fatty Acids)
RN  - 0 (Fatty Acids, Monounsaturated)
RN  - 0 (Lipoproteins)
RN  - 0 (Triglycerides)
RN  - 97C5T2UQ7J (Cholesterol)
SB  - IM
MH  - Adult
MH  - Body Mass Index
MH  - Body Weight
MH  - Cholesterol/blood
MH  - Cholesterol, HDL/blood
MH  - Cholesterol, LDL/blood
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Dietary Fats, Unsaturated/*administration & dosage
MH  - Erythrocyte Membrane/chemistry
MH  - Fatty Acids/blood
MH  - Fatty Acids, Monounsaturated/*administration & dosage
MH  - Humans
MH  - Lipid Peroxidation
MH  - Lipoproteins/*blood
MH  - Male
MH  - Random Allocation
MH  - Triglycerides/blood
EDAT- 1992/08/01 00:00
MHDA- 1992/08/01 00:01
CRDT- 1992/08/01 00:00
PHST- 1992/08/01 00:00 [pubmed]
PHST- 1992/08/01 00:01 [medline]
PHST- 1992/08/01 00:00 [entrez]
AID - 10.1093/ajcn/56.2.394 [doi]
PST - ppublish
SO  - Am J Clin Nutr. 1992 Aug;56(2):394-403. doi: 10.1093/ajcn/56.2.394.