PMID- 16372385
OWN - NLM
STAT- MEDLINE
DCOM- 20060323
LR  - 20061115
IS  - 0951-4198 (Print)
IS  - 0951-4198 (Linking)
VI  - 20
IP  - 3
DP  - 2006
TI  - Validation of a gas chromatography/triple quadrupole mass spectrometry based 
      method for the quantification of pesticides in food commodities.
PG  - 365-75
AB  - A new multiresidue method has been validated in cucumber matrix for the routine 
      analysis of 130 multiclass pesticide residues by gas chromatography/triple 
      quadrupole mass spectrometry. The pesticides were extracted with ethyl acetate. A 
      first identification of the pesticides was based on a tandem mass spectrometric 
      (MS/MS) screening method, which monitors a single transition for each target 
      compound, in less than 12 min. After that, potentially non-negative samples were 
      analyzed again by the MS/MS confirmation/quantification method, which monitors 
      two or three MS/MS transitions for each compound, also in less than 12 min. 
      Performance characteristics, such as trueness, precision, linear range, detection 
      limit (LOD) and quantification limit (LOQ), for each pesticide were calculated. 
      The average recoveries obtained ranged between 70 and 120% at three different 
      fortification levels (25, 200 and 500 microg/kg) with precision, expressed as 
      relative standard deviation (RSD), values lower than 15%. The calculated LOD and 
      LOQ were typically <3.2 and 9.6 microg/kg, respectively. Such limits were much 
      lower than the maximum residue levels (MRLs) established by European legislation. 
      The proposed methodology was applied to the determination of pesticides in real 
      vegetable samples from Almeria (Spain).
CI  - Copyright (c) 2005 John Wiley & Sons, Ltd
FAU - Martinez Vidal, J L
AU  - Martinez Vidal JL
AD  - Department of Analytical Chemistry, University of Almeria, 04071 Almeria, Spain.
FAU - Arrebola Liebanas, F J
AU  - Arrebola Liebanas FJ
FAU - Gonzalez Rodriguez, M J
AU  - Gonzalez Rodriguez MJ
FAU - Garrido Frenich, A
AU  - Garrido Frenich A
FAU - Fernandez Moreno, J L
AU  - Fernandez Moreno JL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Rapid Commun Mass Spectrom
JT  - Rapid communications in mass spectrometry : RCM
JID - 8802365
RN  - 0 (Pesticides)
SB  - IM
MH  - Calibration
MH  - Food Contamination/*analysis
MH  - Gas Chromatography-Mass Spectrometry
MH  - Molecular Structure
MH  - Pesticides/*analysis/isolation & purification
MH  - Reference Standards
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Vegetables/chemistry
EDAT- 2005/12/24 09:00
MHDA- 2006/03/24 09:00
CRDT- 2005/12/24 09:00
PHST- 2005/12/24 09:00 [pubmed]
PHST- 2006/03/24 09:00 [medline]
PHST- 2005/12/24 09:00 [entrez]
AID - 10.1002/rcm.2315 [doi]
PST - ppublish
SO  - Rapid Commun Mass Spectrom. 2006;20(3):365-75. doi: 10.1002/rcm.2315.