PMID- 16376905
OWN - NLM
STAT- MEDLINE
DCOM- 20060526
LR  - 20131121
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 1107
IP  - 1-2
DP  - 2006 Feb 24
TI  - Determination of bisphenol diglycidyl ether residues in canned foods by 
      pressurized liquid extraction and liquid chromatography-tandem mass spectrometry.
PG  - 70-8
AB  - A new confirmatory method for simultaneous determination of bisphenol diglycidyl 
      ether residues (BADGE, BADGE.H(2)O, BADGE.2H(2)O, BADGE.H(2)O.HCl, BADGE.HCl, 
      BADGE.2HCl, BFDGE and BFDGE.2HCl) from canned food has been developed. The 
      proposed method includes extraction by pressurized liquid extraction (PLE) 
      followed by liquid-liquid partition and purification by solid phase extraction 
      (SPE). Several solvent systems and different operating conditions (time, 
      temperature) have been investigated for PLE optimization. A reversed-phase 
      high-performance liquid chromatography (RP-HPLC) coupled to atmospheric pressure 
      chemical ionisation tandem mass spectrometry (APCI-MS-MS) method was developed 
      for the separation, quantification and confirmation. The ion source settings were 
      optimized using a design of experiments (DOE). The optimized method was applied 
      to the determination of these chemicals at very low levels in different samples 
      with a quantification limit of 5 ng/g. Recoveries ranged between 82 and 101% and 
      standard deviations were less than 10%.
FAU - Pardo, Olga
AU  - Pardo O
AD  - Public Health Laboratory of Valencia, Conselleria de Sanitat, Cami de la Marjal, 
      s/n 46470 Albal, Valencia, Spain.
FAU - Yusa, Vicent
AU  - Yusa V
FAU - Leon, Nuria
AU  - Leon N
FAU - Pastor, Agustin
AU  - Pastor A
LA  - eng
PT  - Journal Article
DEP - 20051227
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Benzhydryl Compounds)
RN  - 0 (Epoxy Compounds)
RN  - 0 (Solvents)
RN  - F3XRM1NX4H (2,2-bis(4-glycidyloxyphenyl)propane)
SB  - IM
MH  - Atmospheric Pressure
MH  - Benzhydryl Compounds
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Epoxy Compounds/*analysis
MH  - *Food Analysis
MH  - Mass Spectrometry/*methods
MH  - Solvents
MH  - Temperature
EDAT- 2005/12/27 09:00
MHDA- 2006/05/27 09:00
CRDT- 2005/12/27 09:00
PHST- 2005/07/29 00:00 [received]
PHST- 2005/11/24 00:00 [revised]
PHST- 2005/11/29 00:00 [accepted]
PHST- 2005/12/27 09:00 [pubmed]
PHST- 2006/05/27 09:00 [medline]
PHST- 2005/12/27 09:00 [entrez]
AID - S0021-9673(05)02375-7 [pii]
AID - 10.1016/j.chroma.2005.11.128 [doi]
PST - ppublish
SO  - J Chromatogr A. 2006 Feb 24;1107(1-2):70-8. doi: 10.1016/j.chroma.2005.11.128. 
      Epub 2005 Dec 27.