PMID- 16383181
OWN - NLM
STAT- MEDLINE
DCOM- 20060209
LR  - 20131121
IS  - 0730-0832 (Print)
IS  - 0730-0832 (Linking)
VI  - 24
IP  - 6
DP  - 2005 Nov-Dec
TI  - Intravenous immunoglobulin in the management of hemolytic disease of the newborn.
PG  - 17-24
AB  - Jaundice caused by hemolysis continues to challenge practitioners caring for 
      infants in the NICU. Bilirubin levels can rise quickly in the first days of life, 
      and interventions must be prompt to prevent side effects related to 
      hyperbilirubinemia. Conventional treatments such as hydration and phototherapy 
      are common, but new studies suggest that use of intravenous immunoglobin (IVIG) 
      as an additional treatment may prevent the need for exchange transfusion in some 
      babies. This article presents a case study of an infant with blood-type 
      incompatibility treated successfully with multiple doses of IVIG, discusses the 
      pathophysiology and clinical presentation of hemolytic jaundice, and reviews 
      current management strategies for this disease.
FAU - Mundy, Cynthia A
AU  - Mundy CA
AD  - School of Nursing, Medical College of Georgia, Augusta 30912, USA. cmundy@mcg.edu
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Neonatal Netw
JT  - Neonatal network : NN
JID - 8503921
RN  - 0 (ABO Blood-Group System)
RN  - 0 (Immunoglobulins, Intravenous)
RN  - 0 (Immunologic Factors)
RN  - 0 (Metalloporphyrins)
RN  - RFM9X3LJ49 (Bilirubin)
MH  - ABO Blood-Group System
MH  - Adult
MH  - Bilirubin/blood
MH  - Blood Group Incompatibility/complications
MH  - Clinical Protocols
MH  - Drug Monitoring
MH  - Erythroblastosis, Fetal/blood/etiology/*therapy
MH  - Exchange Transfusion, Whole Blood
MH  - Female
MH  - Hematocrit
MH  - Humans
MH  - Immunoglobulins, Intravenous/*therapeutic use
MH  - Immunologic Factors/*therapeutic use
MH  - Infant, Newborn
MH  - Infusions, Intravenous
MH  - Jaundice, Neonatal/etiology
MH  - Metalloporphyrins/therapeutic use
MH  - Neonatal Nursing
MH  - Nurse's Role
MH  - Phototherapy
MH  - Pregnancy
MH  - Rh Isoimmunization/complications
RF  - 23
EDAT- 2005/12/31 09:00
MHDA- 2006/02/10 09:00
CRDT- 2005/12/31 09:00
PHST- 2005/12/31 09:00 [pubmed]
PHST- 2006/02/10 09:00 [medline]
PHST- 2005/12/31 09:00 [entrez]
AID - 10.1891/0730-0832.24.6.17 [doi]
PST - ppublish
SO  - Neonatal Netw. 2005 Nov-Dec;24(6):17-24. doi: 10.1891/0730-0832.24.6.17.