PMID- 16388380
OWN - NLM
STAT- MEDLINE
DCOM- 20060412
LR  - 20220330
IS  - 0957-4530 (Print)
IS  - 0957-4530 (Linking)
VI  - 16
IP  - 11
DP  - 2005 Nov
TI  - Effects of hydrothermal treatment with CaCl(2) solution on surface property and 
      cell response of titanium implants.
PG  - 985-91
AB  - In order to obtain early and good osteointegration after implantation of a 
      titanium implant in the human body, the surface modified treatments using NaOH or 
      H(2)O(2) etc. were reported. In this study, titanium was hydrothermally treated 
      with CaCl(2) solutions at 200 degrees C for 24hr (CaCl(2)-HT). Scanning electron 
      microscope (SEM) observation clearly showed apatite deposition on the surface of 
      CaCl(2) HT treated titanium faster than other chemical treated titanium immersion 
      in simulated body fluid. X-ray photoelectron spectroscopy (XPS) analysis 
      demonstrated that Ti--O--Ca bonding was formed on titanium surface by 
      hydrothermal treatment with CaCl(2) solution. And it was revealed that thickness 
      of TiO(2), which was known to play important roles for the formation of bone-like 
      apatite, became approximately three times thicker than as-polished titanium. The 
      amount of initial attached MC3T3-E1 cells on as-polished and NaOH, H(2)O(2) and 
      this CaCl(2) HT treated titanium were almost the same values. After 5 days 
      incubation, the growth rate of MC3T3-E1 cells on CaCl(2)-HT treated titanium was 
      significantly higher than that on other chemical treated titanium. The 
      hydrothermal treatment with 10-20 mmol/L CaCl(2) solution at 200 degrees C was an 
      effective method for the fabrication of titanium implant with good bioactivity 
      and osteoconductivity.
FAU - Nakagawa, M
AU  - Nakagawa M
AD  - Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 
      Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. nakagawa@dent.kyushu-u.ac.jp
FAU - Zhang, L
AU  - Zhang L
FAU - Udoh, K
AU  - Udoh K
FAU - Matsuya, S
AU  - Matsuya S
FAU - Ishikawa, K
AU  - Ishikawa K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Mater Sci Mater Med
JT  - Journal of materials science. Materials in medicine
JID - 9013087
RN  - 059QF0KO0R (Water)
RN  - 27YLU75U4W (Phosphorus)
RN  - D1JT611TNE (Titanium)
RN  - M4I0D6VV5M (Calcium Chloride)
RN  - SY7Q814VUP (Calcium)
SB  - IM
MH  - 3T3 Cells
MH  - Animals
MH  - Body Fluids/*chemistry
MH  - Calcium/metabolism
MH  - Calcium Chloride/*chemistry
MH  - Cell Adhesion
MH  - Cell Proliferation
MH  - Mice
MH  - Microscopy, Electron, Scanning
MH  - Phosphorus/metabolism
MH  - *Prostheses and Implants
MH  - *Surface Properties
MH  - Temperature
MH  - Titanium/*chemistry
MH  - Water/chemistry
MH  - X-Ray Diffraction
EDAT- 2006/01/03 09:00
MHDA- 2006/04/13 09:00
CRDT- 2006/01/03 09:00
PHST- 2005/03/22 00:00 [received]
PHST- 2005/05/25 00:00 [accepted]
PHST- 2006/01/03 09:00 [pubmed]
PHST- 2006/04/13 09:00 [medline]
PHST- 2006/01/03 09:00 [entrez]
AID - 10.1007/s10856-005-4753-0 [doi]
PST - ppublish
SO  - J Mater Sci Mater Med. 2005 Nov;16(11):985-91. doi: 10.1007/s10856-005-4753-0.