PMID- 16403266
OWN - NLM
STAT- MEDLINE
DCOM- 20080902
LR  - 20161018
IS  - 1009-2137 (Print)
IS  - 1009-2137 (Linking)
VI  - 13
IP  - 6
DP  - 2005 Dec
TI  - [Effects of RhG-CSF on apoptosis of HL-60 cell induced by cytarabine].
PG  - 996-8
AB  - To investigate the effects of rhG-CSF on apoptosis of HL-60 cell induced by 
      cytarabine (Ara-C), HL-60 cell were cultured with Ara-C, with or without rhG-CSF, 
      and the changes of HL-60 cells were detected by morphology, including Wright's 
      and acridine orange (AO) and ethidium bromide (EB) staining, and MTT assay. The 
      results showed that comparing with Ara-C group, the apoptosis level of rhG-CSF + 
      Ara-C group was enhanced (P < 0.01), and the OD value of MTT assay declined (P < 
      0.01). It is concluded that rhG-CSF can induce the apoptosis of HL-60 cells and 
      enhance the apoptosis induced by Ara-C.
FAU - Wang, Hong
AU  - Wang H
AD  - Department of Pediactrics, Affiliated Hospital of Qingdao University, Qingdao 
      266003 China.
FAU - Sun, Li-Rong
AU  - Sun LR
FAU - Li, Li
AU  - Li L
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhongguo Shi Yan Xue Ye Xue Za Zhi
JT  - Zhongguo shi yan xue ye xue za zhi
JID - 101084424
RN  - 0 (Antimetabolites, Antineoplastic)
RN  - 0 (Recombinant Proteins)
RN  - 04079A1RDZ (Cytarabine)
RN  - 143011-72-7 (Granulocyte Colony-Stimulating Factor)
SB  - IM
MH  - Antimetabolites, Antineoplastic/pharmacology
MH  - Apoptosis/*drug effects
MH  - Cell Survival/drug effects
MH  - Cytarabine/*pharmacology
MH  - Drug Synergism
MH  - Granulocyte Colony-Stimulating Factor/*pharmacology
MH  - HL-60 Cells
MH  - Humans
MH  - Recombinant Proteins
EDAT- 2006/01/13 09:00
MHDA- 2008/09/03 09:00
CRDT- 2006/01/13 09:00
PHST- 2006/01/13 09:00 [pubmed]
PHST- 2008/09/03 09:00 [medline]
PHST- 2006/01/13 09:00 [entrez]
AID - 1009-2137(2005)06-0996-03 [pii]
PST - ppublish
SO  - Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2005 Dec;13(6):996-8.