PMID- 16419133
OWN - NLM
STAT- MEDLINE
DCOM- 20060323
LR  - 20200930
IS  - 1552-4825 (Print)
IS  - 1552-4825 (Linking)
VI  - 140
IP  - 4
DP  - 2006 Feb 15
TI  - A subterminal deletion of the long arm of chromosome 10: a clinical report and 
      review.
PG  - 402-9
AB  - We report on a girl with mental retardation, dysmorphic features, and behavioral 
      problems. A small terminal deletion of the long arm of chromosome 10 was detected 
      by subtelomeric fluorescence in situ hybridization (FISH) studies in all analyzed 
      metaphases. The deletion was shown to be a de novo terminal deletion of 
      approximately 6.1 Mb, with the deletion breakpoint localized at band 10q26.2, 
      between BAC probes RP11-498K22 and RP11-42K2. A subterminal 10q deletion as found 
      in the present patient has, to our knowledge, only been reported in 15 patients 
      (including 8 familial cases). We review the clinical and behavioral phenotype of 
      these patients with "pure" subterminal 10q deletion.
CI  - Copyright (c) 2006 Wiley-Liss, Inc.
FAU - Courtens, Winnie
AU  - Courtens W
AD  - Department of Medical Genetics, University Hospital Antwerp, Antwerp, Belgium. 
      winnie.courtens@ua.ac.be
FAU - Wuyts, Wim
AU  - Wuyts W
FAU - Rooms, Liesbeth
AU  - Rooms L
FAU - Pera, Sarah Barbera
AU  - Pera SB
FAU - Wauters, Jan
AU  - Wauters J
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Am J Med Genet A
JT  - American journal of medical genetics. Part A
JID - 101235741
SB  - IM
MH  - Adult
MH  - Child Behavior Disorders/genetics/pathology
MH  - Child, Preschool
MH  - *Chromosome Deletion
MH  - Chromosomes, Human, Pair 10/*genetics
MH  - Face/abnormalities
MH  - Female
MH  - Growth Disorders/*genetics/pathology
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Intellectual Disability/*genetics/pathology
MH  - Male
EDAT- 2006/01/19 09:00
MHDA- 2006/03/24 09:00
CRDT- 2006/01/19 09:00
PHST- 2006/01/19 09:00 [pubmed]
PHST- 2006/03/24 09:00 [medline]
PHST- 2006/01/19 09:00 [entrez]
AID - 10.1002/ajmg.a.31053 [doi]
PST - ppublish
SO  - Am J Med Genet A. 2006 Feb 15;140(4):402-9. doi: 10.1002/ajmg.a.31053.