PMID- 16421972 OWN - NLM STAT- MEDLINE DCOM- 20060517 LR - 20181113 IS - 1673-1581 (Print) IS - 1673-1581 (Linking) VI - 7 IP - 2 DP - 2006 Feb TI - Surgical outcomes and strategy of hypertrophic obstructive cardiomyopathy. PG - 148-53 AB - OBJECTIVE: To evaluate the surgical clinical results of hypertrophic obstructive cardiomyopathy. METHODS: We retrospectively collected data on 24 patients who underwent surgical management in the past ten years in two hospitals in China and Madras Medical Mission in India. Myomectomy was carried out on all patients. Among them 3 patients underwent mitral valve replacement; 2 patients underwent mitral valve repair (anterior mitral leaflet plication); 2 patients underwent aortic valve replacement; 1 patient underwent aortic valve repair; 2 patients underwent aortic root replacement; 1 patient underwent Bentall's procedure and 1 patient underwent coronary artery bypass grafting because of a breached muscle bridge. RESULTS: One patient died of post-operative heart failure. The mean follow-up time was 4.3 years. There was significant improvement in the symptomatic status. Sixteen patients were asymptomatic with good effort tolerance and only four patients had New York heart association (NYHA) Classes I-II due to associated valvular lesions. CONCLUSION: Our experience proved that symptomatic hypertrophic obstructive cardiomyopathy or non-symptomatic hypertrophic obstructive cardiomyopathy with combined heart disease is indication for surgery as surgical intervention could get better clinical results in this kind of patients compared with other non-surgical method because it beneficially reduces the systolic anterior motion (SAM) of the mitral valve leaflet, which could not be avoided by other non-surgical treatment. FAU - Zhu, Ya-bin AU - Zhu YB AD - Department of Thoracic and Cardiovascular Surgery, Affiliated Su Bei Hospital, Yangzhou University, Yangzhou 225001, China. b4878375@163.com FAU - Rajan, S AU - Rajan S FAU - Kurian, V M AU - Kurian VM FAU - Liu, Zhi-yong AU - Liu ZY LA - eng PT - Journal Article PL - China TA - J Zhejiang Univ Sci B JT - Journal of Zhejiang University. Science. B JID - 101236535 SB - IM MH - Adolescent MH - Adult MH - Aortic Valve/surgery/transplantation MH - *Cardiac Surgical Procedures MH - Cardiomyopathy, Hypertrophic/*surgery MH - China MH - Coronary Artery Bypass MH - Female MH - Heart Valve Prosthesis MH - Heart Valve Prosthesis Implantation/*methods MH - Humans MH - India MH - Male MH - Middle Aged MH - Mitral Valve/pathology/surgery/transplantation MH - Treatment Outcome PMC - PMC1363760 EDAT- 2006/01/20 09:00 MHDA- 2006/05/18 09:00 PMCR- 2006/02/01 CRDT- 2006/01/20 09:00 PHST- 2006/01/20 09:00 [pubmed] PHST- 2006/05/18 09:00 [medline] PHST- 2006/01/20 09:00 [entrez] PHST- 2006/02/01 00:00 [pmc-release] AID - 10.1631/jzus.2006.B0148 [doi] PST - ppublish SO - J Zhejiang Univ Sci B. 2006 Feb;7(2):148-53. doi: 10.1631/jzus.2006.B0148.