PMID- 16440145
OWN - NLM
STAT- MEDLINE
DCOM- 20070815
LR  - 20220716
IS  - 0910-8327 (Print)
IS  - 0910-8327 (Linking)
VI  - 21
IP  - 1
DP  - 2006 Jan
TI  - Mitral valve annuloplasty and myocardial revascularization in the treatment of 
      ischemic dilated cardiomyopathy.
PG  - 28-32
AB  - The aim of this study was to examine perioperative mortality and morbidity and 
      midterm results in patients undergoing coronary bypass graft and mitral valve 
      annuloplasty with advanced dilated cardiomyopathy. Sixty-one patients with 
      ischemic dilated cardiomyopathy underwent coronary artery bypass grafting and 
      mitral valve annuloplasty between January 1998 and December 2003. Patients 
      eligible for revascularization that presented a mild or more severe mitral valve 
      regurgitation at echocardiography (effective regurgitant orifice > 0.2 cm(2)) 
      were considered for annuloplasty with a Cosgrove ring. New York Heart Association 
      class (NYHA) III/IV was present in 40 patients (66%) and Canadian Cardiovascular 
      Society class III-IV in 19 (31%). A previous acute myocardial infarction was 
      reported in 48 patients (79%). The mean number of graft anastomoses was 2.5 +/- 
      0.7 and the left internal mammary artery was used in 49 patients (80%). 
      In-hospital mortality was 4.9% (3 patients), due to unsuccessful weaning from 
      cardiopulmonary bypass, multiple organ failure, and stroke, respectively. Left 
      ventricle ejection fraction improved from 28.9% +/- 5.2% preoperatively to 35.4% 
      +/- 8.1% at follow-up (P = 0.0001) and a significant reduction in NYHA III/IV was 
      detected: from 40 patients preoperatively (66%) to 14 (31%) at follow-up (P = 
      0.031). Midterm cardiac-related mortality rate was 3.4%. In our experience 
      combined coronary artery bypass grafting and ring annuloplasty for ischemic 
      dilated cardiomyopathy can be performed with acceptable risks for in-hospital 
      mortality and morbidity. Midterm results show a good survival rate and a durable 
      functional improvement in this subset of patients.
FAU - Nicolini, Francesco
AU  - Nicolini F
AD  - Cardiac Surgery Department, University of Parma, Parma, Italy. 
      francesconicolini@libero.it
FAU - Zoffoli, Giampaolo
AU  - Zoffoli G
FAU - Cagnoni, Giovanni
AU  - Cagnoni G
FAU - Agostinelli, Andrea
AU  - Agostinelli A
FAU - Colli, Andrea
AU  - Colli A
FAU - Fragnito, Claudio
AU  - Fragnito C
FAU - Borrello, Bruno
AU  - Borrello B
FAU - Beghi, Cesare
AU  - Beghi C
FAU - Gherli, Tiziano
AU  - Gherli T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - Heart Vessels
JT  - Heart and vessels
JID - 8511258
SB  - IM
MH  - Aged
MH  - Cardiomyopathy, Dilated/diagnostic imaging/mortality/physiopathology/*surgery
MH  - *Coronary Artery Bypass
MH  - Echocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - *Heart Valve Prosthesis Implantation
MH  - Hospital Mortality
MH  - Humans
MH  - Internal Mammary-Coronary Artery Anastomosis
MH  - Italy
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Insufficiency/diagnostic imaging/mortality/physiopathology/*surgery
MH  - Myocardial Ischemia/diagnostic imaging/mortality/physiopathology/*surgery
MH  - Severity of Illness Index
MH  - Stroke Volume
MH  - Survival Rate
MH  - Treatment Outcome
MH  - Ventricular Dysfunction, Left/diagnostic 
      imaging/mortality/physiopathology/surgery
EDAT- 2006/01/28 09:00
MHDA- 2007/08/19 09:00
CRDT- 2006/01/28 09:00
PHST- 2005/01/13 00:00 [received]
PHST- 2005/07/23 00:00 [accepted]
PHST- 2006/01/28 09:00 [pubmed]
PHST- 2007/08/19 09:00 [medline]
PHST- 2006/01/28 09:00 [entrez]
AID - 10.1007/s00380-005-0855-3 [doi]
PST - ppublish
SO  - Heart Vessels. 2006 Jan;21(1):28-32. doi: 10.1007/s00380-005-0855-3.