PMID- 16441486
OWN - NLM
STAT- MEDLINE
DCOM- 20060613
LR  - 20111117
IS  - 0001-2815 (Print)
IS  - 0001-2815 (Linking)
VI  - 67
IP  - 2
DP  - 2006 Feb
TI  - HLA-A, -B, and -DRB1 polymorphism defined by sequence-based typing of the Han 
      population in Northern China.
PG  - 146-52
AB  - DNA typing for human leukocyte antigen (HLA)-A, -B and -DRB1 was performed using 
      polymerase chain reaction-sequence-based typing method on 618 randomly selected 
      healthy individuals of the Han population in Northern China. Allele frequencies 
      and haplotypes were statistically analyzed. A total of 84 HLA-A alleles, 143 B 
      alleles, and 122 DRB1 alleles were detected, and 853 A-B-DRB1 haplotypes, 473 A-B 
      haplotypes, and 551 B-DRB1 haplotypes were statistically inferred. Statistical 
      analysis of three-locus haplotypes showed that A*0207-B*4601-DRB1*0901 (3.06%) 
      was the most predominant. Gene frequencies and haplotypic associations within 
      HLA-A, -B, and -DRB1 loci were determined at a high-resolution (four digit) 
      allelic level and should provide useful information in anthropology, bone marrow 
      donor registry, legal medicine, and disease association studies.
FAU - Yang, G
AU  - Yang G
AD  - The National Laboratory of the Ministry of Health for Forensic Sciences, Xi'an 
      Jiaotong University, Xi'an, China.
FAU - Deng, Y-J
AU  - Deng YJ
FAU - Hu, S-N
AU  - Hu SN
FAU - Wu, D-Y
AU  - Wu DY
FAU - Li, S-B
AU  - Li SB
FAU - Zhu, J
AU  - Zhu J
FAU - Zhu, B-F
AU  - Zhu BF
FAU - Liu, Y
AU  - Liu Y
LA  - eng
PT  - Journal Article
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-DR Antigens)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - Alleles
MH  - China/epidemiology
MH  - Gene Frequency
MH  - Genetic Variation
MH  - HLA-A Antigens/*genetics
MH  - HLA-B Antigens/*genetics
MH  - HLA-DR Antigens/*genetics
MH  - HLA-DRB1 Chains
MH  - Haplotypes
MH  - Humans
MH  - Polymerase Chain Reaction/methods
MH  - *Polymorphism, Genetic
MH  - *Sequence Analysis, DNA
EDAT- 2006/01/31 09:00
MHDA- 2006/06/14 09:00
CRDT- 2006/01/31 09:00
PHST- 2006/01/31 09:00 [pubmed]
PHST- 2006/06/14 09:00 [medline]
PHST- 2006/01/31 09:00 [entrez]
AID - TAN529 [pii]
AID - 10.1111/j.1399-0039.2006.00529.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2006 Feb;67(2):146-52. doi: 10.1111/j.1399-0039.2006.00529.x.