PMID- 16442341
OWN - NLM
STAT- MEDLINE
DCOM- 20060525
LR  - 20080910
IS  - 1388-2457 (Print)
IS  - 1388-2457 (Linking)
VI  - 117
IP  - 3
DP  - 2006 Mar
TI  - Within-subject reliability of motor unit number estimates and quantitative motor 
      unit analysis in a distal and proximal upper limb muscle.
PG  - 596-603
AB  - OBJECTIVE: To establish within-subject reliability of motor unit number estimates 
      (MUNEs) and quantitative MU analysis using decomposition-based quantitative 
      electromyography (DQEMG). METHODS: Following the acquisition of a maximum M-wave, 
      needle and surface-detected EMG signals were collected during contractions of the 
      first dorsal interrosseous (FDI) and biceps brachii (BB). DQEMG was used to 
      extract motor unit potential (MUP) trains and surface-detected MUPs associated 
      with each train, the mean size of which was divided into the maximum M-wave to 
      obtain a MUNE. Retests were performed following the initial test to evaluate 
      reliability. RESULTS: Subjects test-retest MUNEs were highly correlated (r=0.72 
      FDI; 0.97 BB) with no significant differences between test and retest MUNE values 
      (P>0.10). Ninety-five percent confidence intervals were calculated to establish 
      the range of expected retest MUNE variability and were +/-41 MUs for the FDI and 
      BB. Quantitative information pertaining to MU size, complexity and firing rate 
      were similar for both tests. CONCLUSION: MUNEs and quantitative MU data can be 
      obtained reliably from the BB and FDI using DQEMG in individual subjects. 
      SIGNIFICANCE: Establishing within-subject reliability of MUNEs and quantitative 
      MU analysis allow clinicians to longitudinally follow changes in the MU pool of 
      individuals with disorders of the central or peripheral nervous system in 
      addition to assessing their response to treatments.
FAU - Boe, Shaun G
AU  - Boe SG
AD  - School of Kinesiology, The University of Western Ontario, Ont., Canada.
FAU - Stashuk, Daniel W
AU  - Stashuk DW
FAU - Doherty, Timothy J
AU  - Doherty TJ
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20060125
PL  - Netherlands
TA  - Clin Neurophysiol
JT  - Clinical neurophysiology : official journal of the International Federation of 
      Clinical Neurophysiology
JID - 100883319
SB  - IM
MH  - Adult
MH  - Electric Stimulation/methods
MH  - Electromyography/methods
MH  - Evoked Potentials, Motor/*physiology
MH  - Humans
MH  - Motor Neurons/*physiology
MH  - Muscle Contraction/physiology
MH  - Muscle, Skeletal/*cytology/physiology
MH  - Reproducibility of Results
MH  - Upper Extremity/*innervation
EDAT- 2006/01/31 09:00
MHDA- 2006/05/26 09:00
CRDT- 2006/01/31 09:00
PHST- 2005/08/23 00:00 [received]
PHST- 2005/10/11 00:00 [revised]
PHST- 2005/10/30 00:00 [accepted]
PHST- 2006/01/31 09:00 [pubmed]
PHST- 2006/05/26 09:00 [medline]
PHST- 2006/01/31 09:00 [entrez]
AID - S1388-2457(05)00454-2 [pii]
AID - 10.1016/j.clinph.2005.10.021 [doi]
PST - ppublish
SO  - Clin Neurophysiol. 2006 Mar;117(3):596-603. doi: 10.1016/j.clinph.2005.10.021. 
      Epub 2006 Jan 25.