PMID- 16445606
OWN - NLM
STAT- MEDLINE
DCOM- 20060517
LR  - 20220321
IS  - 1048-891X (Print)
IS  - 1048-891X (Linking)
VI  - 16
IP  - 1
DP  - 2006 Jan-Feb
TI  - A 10-year review of primary fallopian tube cancer at a community hospital: a high 
      association of synchronous and metachronous cancers.
PG  - 29-35
AB  - Primary fallopian tube carcinomas (PFTC) are rare gynecological tumors 
      infrequently diagnosed prior to operative intervention. A retrospective review 
      was performed to characterize the distribution and clinicopathologic significance 
      of these tumors. Identification of PFTC was achieved through a review of the 
      tumor registry and medical record ICD-9 codes at a community teaching hospital. A 
      total of 1.5% of all gynecological cancers were PFTC. Most patients were presumed 
      to have ovarian cancer. Ultrasound had the highest sensitivity (82%) for 
      preoperative diagnosis. Surgical exploration was needed for definitive diagnosis 
      in all patients. Optimal debulking was predictive of survival and of a negative 
      second-look laparotomy (P < 0.05). Twenty-five percent of patients had a 
      metachronous cancer diagnosed prior to their fallopian tube cancer, and 22% had a 
      synchronous gynecological malignancy diagnosed at the time of surgical 
      exploration. The response rate to platinum-based chemotherapy was 78%. The 5-year 
      survival rate was 87%, and the overall survival rate was 75%. The median 
      follow-up was 38 months. This report details the diagnostic and therapeutic 
      experience of patients with PFTC and describes the occurrence of synchronous and 
      metachronous gynecological cancers.
FAU - Benoit, M F
AU  - Benoit MF
AD  - Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The 
      University of Texas Medical Branch, 301 University Boulevard, Route 0587, 
      Galveston, TX 77555, USA. mibenoit@utmb.edu
FAU - Hannigan, E V
AU  - Hannigan EV
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Int J Gynecol Cancer
JT  - International journal of gynecological cancer : official journal of the 
      International Gynecological Cancer Society
JID - 9111626
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Carcinoma/*mortality/*pathology/therapy
MH  - Carcinoma, Transitional Cell/mortality/pathology/therapy
MH  - Combined Modality Therapy
MH  - Fallopian Tube Neoplasms/*mortality/*pathology/therapy
MH  - Female
MH  - Hospitals, Community
MH  - Humans
MH  - Immunohistochemistry
MH  - Incidence
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Neoplasms, Multiple Primary/*mortality/*pathology/therapy
MH  - Neoplasms, Second Primary/mortality/pathology/therapy
MH  - Prognosis
MH  - Registries
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Survival Analysis
MH  - Teratoma/mortality/pathology/therapy
EDAT- 2006/02/01 09:00
MHDA- 2006/05/18 09:00
CRDT- 2006/02/01 09:00
PHST- 2006/02/01 09:00 [pubmed]
PHST- 2006/05/18 09:00 [medline]
PHST- 2006/02/01 09:00 [entrez]
AID - IJG292 [pii]
AID - 10.1111/j.1525-1438.2006.00292.x [doi]
PST - ppublish
SO  - Int J Gynecol Cancer. 2006 Jan-Feb;16(1):29-35. doi: 
      10.1111/j.1525-1438.2006.00292.x.