PMID- 16448159
OWN - NLM
STAT- MEDLINE
DCOM- 20060328
LR  - 20131121
IS  - 0021-8561 (Print)
IS  - 0021-8561 (Linking)
VI  - 54
IP  - 3
DP  - 2006 Feb 8
TI  - Ethanol/Water extraction combined with solid-phase extraction and solid-phase 
      microextraction concentration for the determination of chlorophenols in cork 
      stoppers.
PG  - 627-32
AB  - The appearance of 2,4,6-trichloroanisole (TCA) in cork stoppers is of great 
      concern because it can cause off-flavors in bottled wine. To prevent this 
      sensorial defect, there should not be any traces of 2,4,6-trichlorophenol (TCP), 
      2,3,4,6-tetrachlorophenol (TeCP), or pentachlorophenol (PCP) in the finished 
      corks, because they are the direct precursors of TCA. In the course of this study 
      two methodologies based upon an extraction with ethanol/water mixtures to 
      determine the chlorophenolic content in cork matrices were developed. The cork 
      extract is preconcentrated using both solid-phase extraction and solid-phase 
      microextraction methodologies. The latter was optimized by applying a full 
      two-level factorial design. Finally, spiked ground corks at nanogram per gram 
      levels of each chlorophenol were analyzed under optimal conditions and by 
      applying both procedures. The obtained results demonstrate that chlorophenols can 
      be detected in corks contaminated at the nanogram per gram level and, thus, these 
      approaches can be successfully applied as quality control measures in the cork 
      industry.
FAU - Insa, Sara
AU  - Insa S
AD  - Department of Chemistry, University of Girona, Campus Montilivi, 17071 Girona, 
      Spain.
FAU - Besalu, Emili
AU  - Besalu E
FAU - Iglesias, Cristina
AU  - Iglesias C
FAU - Salvado, Victoria
AU  - Salvado V
FAU - Antico, Enriqueta
AU  - Antico E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Chlorophenols)
RN  - 059QF0KO0R (Water)
RN  - 3K9958V90M (Ethanol)
SB  - IM
MH  - Chlorophenols/*analysis
MH  - Chromatography, Gas/methods
MH  - Ethanol
MH  - Food Packaging/*instrumentation
MH  - Osmolar Concentration
MH  - Quality Control
MH  - Temperature
MH  - Time Factors
MH  - Water
MH  - Wine/*analysis
EDAT- 2006/02/02 09:00
MHDA- 2006/03/29 09:00
CRDT- 2006/02/02 09:00
PHST- 2006/02/02 09:00 [pubmed]
PHST- 2006/03/29 09:00 [medline]
PHST- 2006/02/02 09:00 [entrez]
AID - 10.1021/jf0512398 [doi]
PST - ppublish
SO  - J Agric Food Chem. 2006 Feb 8;54(3):627-32. doi: 10.1021/jf0512398.