PMID- 16450569
OWN - NLM
STAT- MEDLINE
DCOM- 20060411
LR  - 20171116
IS  - 1088-5412 (Print)
IS  - 1088-5412 (Linking)
VI  - 26
IP  - 5
DP  - 2005 Sep-Oct
TI  - Modern prevalence of insect sensitization in rural asthma and allergic rhinitis 
      patients.
PG  - 356-60
AB  - Inhalant allergy to insects other than cockroaches and dust mites was described 
      in the 1950s, but little attention has been paid to these findings. Sensitization 
      rates for many allergens have increased since then. In this rural population, we 
      describe the current prevalence of sensitization to commonly found insects. We 
      evaluated 200 patients (38 adults and 162 children), for immunoglobulin E 
      (IgE)-mediated sensitization to the caddis fly, mayfly, moth, carpenter ant, and 
      housefly using the prick technique and commercially available whole-body 
      extracts. All had symptoms consistent with asthma and/or allergic rhinitis. They 
      also were tested to indoor and outdoor aeroantigens. Of the 200 patients, 60 
      patients (30%) tested positive to at least one of the five insects. The most 
      prevalent positive skin test was to the mayfly (37/60), followed by the housefly 
      (36/60), caddis fly (27/60), moth (14/60), and ant (10/60). Of the 60 patients 
      positive for insects, 35 patients (58%) also tested positive to at least one 
      species of mite, 36 patients (60%) tested positive to the cockroach. Twelve of 
      the 60 patients (20%) with positive insect testing did not react to either 
      cockroaches or mites. In our patients, the immunoglobulin E-mediated 
      sensitization rate to insects excluding cockroaches is 30%. Many patients also 
      were sensitized to mites and/or cockroaches. These insects are all present in the 
      indoor/outdoor environment of this rural population. Cross-reactivity with mites 
      and cockroaches (insect panallergy) may partially explain our results. The 
      presence of skin test sensitivity in the absence of cockroach or mite allergy 
      suggests possible true insect sensitization.
FAU - Smith, Tamara S
AU  - Smith TS
AD  - Section of Allergy and Immunology, Department of Pediatrics, West Virginia 
      University School of Medicine, Morgantown, West Virginia, USA.
FAU - Hogan, Mary Beth
AU  - Hogan MB
FAU - Welch, Jon E
AU  - Welch JE
FAU - Corder, W Thomas
AU  - Corder WT
FAU - Wilson, Nevin W
AU  - Wilson NW
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Allergy Asthma Proc
JT  - Allergy and asthma proceedings
JID - 9603640
RN  - 0 (Allergens)
SB  - IM
MH  - Adult
MH  - *Allergens
MH  - Animals
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - *Insecta
MH  - Intradermal Tests
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Prospective Studies
MH  - Respiratory Hypersensitivity/*complications/diagnosis/*epidemiology
MH  - *Rural Health
MH  - West Virginia
EDAT- 2006/02/03 09:00
MHDA- 2006/04/12 09:00
CRDT- 2006/02/03 09:00
PHST- 2006/02/03 09:00 [pubmed]
PHST- 2006/04/12 09:00 [medline]
PHST- 2006/02/03 09:00 [entrez]
PST - ppublish
SO  - Allergy Asthma Proc. 2005 Sep-Oct;26(5):356-60.