PMID- 16458345
OWN - NLM
STAT- MEDLINE
DCOM- 20060814
LR  - 20060612
IS  - 0045-6535 (Print)
IS  - 0045-6535 (Linking)
VI  - 64
IP  - 2
DP  - 2006 Jun
TI  - An intercalibration study on organobromine compounds: Results on polybrominated 
      diphenylethers and related dioxin-like compounds.
PG  - 234-44
AB  - An intercalibration study on organobromine compounds has been conducted to 
      evaluate the accuracy and reliability in the analysis of brominated flame 
      retardants (BFRs) such as polybrominated diphenyl ethers (PBDEs) and their 
      related compounds like polybrominated and monobromo-polychlorinated 
      dibenzodioxins and -furans (PBDDs/DFs, MoBPCDDs/DFs). This paper reports the 
      results for these compounds in 'Mixed Standard Solutions' and 'Air-Dried 
      Sediment'. The relative standard deviations (RSDs) for PBDEs, PBDDs/DFs and 
      MoBPCDDs/DFs in mixed standard solutions ranged from 9% to 24%, 4% to 20% and 8% 
      to 27%, respectively. The results of this study are better than those reported in 
      earlier international interlaboratory studies due to general improvement in 
      analytical methods and an increasing number of available authentic standards, 
      particularly for PBDEs. In the analysis for higher brominated compounds such as 
      octabromodibenzodioxin, the participants were advised to optimize the calibration 
      curves befitting the range of concentrations found in samples because variation 
      of relative response factors was noted. The results for 'Air-Dried Sediment' were 
      also reasonable with RSDs from 10% to 38% for PBDEs, 8% to 38% for PBDDs/DFs and 
      17% to 36% for MoBPCDDs/DFs. In the sediment sample, possible errors in the 
      sample pretreatment and/or interference by other compounds/impurities were 
      indicated. The concentrations of pentabromodiphenylether, BDE100, varied more 
      than the other PBDE isomers due to its poor separation in some chromatographic 
      conditions. In addition, interference by PBDEs was observed in the analysis for 
      PBDFs. Potential degradation/secondary formulation of PBDEs and PBDFs during the 
      Soxhlet extraction were suggested when copper powder was added into the sediment 
      samples. Inspite of these observations, the results in this study are better than 
      those reported in other interlaboratory studies due to the advice given to 
      participants for improving the results. Compared with the results for PCDDs/DFs 
      (5-23% RSDs) and Co-PCBs (6-24% RSDs), the RSDs for most of the organobromine 
      compounds were high, indicating an immature QA/QC approach for the analysis of 
      PBDEs and related compounds in comparison to common chlorinated dioxins.
FAU - Takahashi, Shin
AU  - Takahashi S
AD  - National Institute for Environmental Studies, Onogawa 16-2, Tsukuba, Ibaraki 
      305-8506, Japan. shint@agr.ehime-u.ac.jp
FAU - Sakai, Shin-Ichi
AU  - Sakai S
FAU - Watanabe, Isao
AU  - Watanabe I
LA  - eng
PT  - Journal Article
DEP - 20060203
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Dioxins)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Flame Retardants)
RN  - 0 (Phenyl Ethers)
RN  - 0 (Polybrominated Biphenyls)
SB  - IM
MH  - Calibration
MH  - Dioxins/*analysis/standards
MH  - Environmental Pollutants/*analysis/standards
MH  - Flame Retardants/*analysis/standards
MH  - Phenyl Ethers/analysis/standards
MH  - Polybrominated Biphenyls/*analysis/standards
MH  - Reference Standards
MH  - Reproducibility of Results
EDAT- 2006/02/07 09:00
MHDA- 2006/08/15 09:00
CRDT- 2006/02/07 09:00
PHST- 2006/02/07 09:00 [pubmed]
PHST- 2006/08/15 09:00 [medline]
PHST- 2006/02/07 09:00 [entrez]
AID - S0045-6535(05)01436-0 [pii]
AID - 10.1016/j.chemosphere.2005.12.008 [doi]
PST - ppublish
SO  - Chemosphere. 2006 Jun;64(2):234-44. doi: 10.1016/j.chemosphere.2005.12.008. Epub 
      2006 Feb 3.