PMID- 16472979
OWN - NLM
STAT- MEDLINE
DCOM- 20060821
LR  - 20220310
IS  - 0899-9007 (Print)
IS  - 0899-9007 (Linking)
VI  - 22
IP  - 4
DP  - 2006 Apr
TI  - Effects of liquid carbohydrate/essential amino acid ingestion on acute hormonal 
      response during a single bout of resistance exercise in untrained men.
PG  - 367-75
AB  - OBJECTIVE: The primary objective of this study was to investigate the influence 
      of nutritive interventions on acute hormonal responses to a single bout of 
      resistance exercise in untrained young men. Specifically, the aim was to 
      determine whether the acute hormonal milieu conducive to enhancing skeletal 
      muscle hypertrophic adaptation to resistance training could be created. The 
      potential role of cortisol in inhibiting training-induced muscle growth is of 
      particular interest, as is whether exercise-induced cortisol release can be 
      attenuated by nutritive interventions. METHODS: After a 4-h fast, 32 subjects 
      performed a single bout of resistance exercise ( approximately 60 min), during 
      which they consumed a 6% carbohydrate (CHO) solution, a 6-g essential amino acid 
      (EAA) mixture, a combined CHO+EAA supplement, or a placebo beverage. Blood 
      samples were collected every 15 min throughout the exercise bout, immediately 
      after exercise, and 15 and 30 min after exercise for analysis of total 
      testosterone, cortisol, growth hormone, insulin, and glucose. RESULTS: No 
      significant change in glucose or insulin was observed for placebo. CHO and 
      CHO+EAA ingestion resulted in significantly (P < 0.001) increased glucose and 
      insulin concentrations above baseline, whereas EAA resulted in significant 
      postexercise increases (P < 0.05) in insulin only. Placebo exhibited a 
      significant increase in cortisol within 30 min (P < 0.01), with a peak increase 
      of 105% (P < 0.001) immediately after exercise, and cortisol remained 54% above 
      baseline at 30 min after exercise (P < 0.05). Conversely, the treatment groups 
      displayed no significant change in cortisol during the exercise bout, with CHO 
      and CHO+EAA finishing 27% (P < 0.01) and 23% (P < 0.05), respectively, below 
      baseline at 30 min after exercise. No between-group differences in 
      exercise-induced growth hormone or testosterone concentrations after nutritive 
      intervention were present. CONCLUSION: These data indicate that CHO and/or EAA 
      ingestion during a single bout of resistance exercise suppresses the 
      exercise-induced cortisol response, in addition to stimulating insulin release. 
      We conclude that the exercise-induced hormonal profile can be influenced by 
      nutritive interventions toward a profile more favorable for anabolism.
FAU - Bird, Stephen P
AU  - Bird SP
AD  - School of Human Movement Studies, Charles Sturt University, Bathurst, New South 
      Wales, Australia. sbirg@csu.edu.au
FAU - Tarpenning, Kyle M
AU  - Tarpenning KM
FAU - Marino, Frank E
AU  - Marino FE
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20060210
PL  - United States
TA  - Nutrition
JT  - Nutrition (Burbank, Los Angeles County, Calif.)
JID - 8802712
RN  - 0 (Amino Acids, Essential)
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Insulin)
RN  - 12629-01-5 (Human Growth Hormone)
RN  - 3XMK78S47O (Testosterone)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Amino Acids, Essential/*pharmacology
MH  - Area Under Curve
MH  - Blood Glucose/analysis
MH  - Dietary Carbohydrates/*pharmacology
MH  - Double-Blind Method
MH  - Human Growth Hormone/blood
MH  - Humans
MH  - Hydrocortisone/*blood/metabolism
MH  - Insulin/*blood/metabolism
MH  - Insulin Secretion
MH  - Male
MH  - Testosterone/blood
MH  - Weight Lifting/*physiology
EDAT- 2006/02/14 09:00
MHDA- 2006/08/22 09:00
CRDT- 2006/02/14 09:00
PHST- 2005/03/31 00:00 [received]
PHST- 2005/09/26 00:00 [revised]
PHST- 2005/11/08 00:00 [accepted]
PHST- 2006/02/14 09:00 [pubmed]
PHST- 2006/08/22 09:00 [medline]
PHST- 2006/02/14 09:00 [entrez]
AID - S0899-9007(05)00346-1 [pii]
AID - 10.1016/j.nut.2005.11.005 [doi]
PST - ppublish
SO  - Nutrition. 2006 Apr;22(4):367-75. doi: 10.1016/j.nut.2005.11.005. Epub 2006 Feb 
      10.