PMID- 16479871
OWN - NLM
STAT- MEDLINE
DCOM- 20060321
LR  - 20161124
IS  - 0010-6178 (Print)
IS  - 0010-6178 (Linking)
VI  - 70
IP  - 1
DP  - 2006 Jan
TI  - Coronary stenting is safe and effective in a high-risk octogenarian patient 
      cohort.
PG  - 15-9
AB  - BACKGROUND: Octogenarians represent an increasing percentage of patients with 
      coronary heart disease and are an inherently high-risk population. We sought to 
      define the immediate and long-term results of coronary stenting in the 
      "real-world" environment of a community teaching hospital. METHODS: One hundred 
      ninety-seven consecutive patients older then 80 years who underwent 214 coronary 
      stent procedures were studied. Each patient had postprocedural serial cardiac 
      enzymes and ECG's collected, and was followed for a minimum of 12 months after 
      the procedure. Procedural success was defined as less than 20% residual stenosis, 
      TIMI 3 flow, and absence of major complications (death, nonfatal myocardial 
      infarction, emergent coronary artery bypass graft surgery and stroke). Sixty-five 
      percent of patients presented with an acute coronary syndrome and 93% were 
      functionally New York Heart Association (NYHA) Class III or IV. RESULTS: 
      Procedural success was 95%. Death during the index hospitalization occurred in 3% 
      of patients. An additional 4.1% of patients died during follow-up. The target 
      vessel revascularization rate (TVR) during follow up was 8.6%. Multivariate 
      analysis of selected angiographic and clinical variables did not reveal any 
      predictors of major cardiac events. CONCLUSIONS: Despite a high-risk clinical and 
      angiographic profile, coronary stenting can be safely performed in octogenarians 
      with a high procedural success rate, low complication rate, and excellent 
      12-month outcome.
FAU - Baklanov, Dmitri V
AU  - Baklanov DV
AD  - Dartmouth Hitchcock Medical Center, Hanover, New Hampshire, USA.
FAU - Marcu, Constantin B
AU  - Marcu CB
FAU - Juhasz, Deanna F
AU  - Juhasz DF
FAU - Caracciolo, Eugene A
AU  - Caracciolo EA
FAU - Chawarski, Marek C
AU  - Chawarski MC
FAU - Donohue, Thomas J
AU  - Donohue TJ
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Conn Med
JT  - Connecticut medicine
JID - 0372745
SB  - IM
MH  - Age Factors
MH  - Aged, 80 and over
MH  - Coronary Angiography
MH  - Coronary Artery Disease/diagnostic imaging/*surgery
MH  - Female
MH  - Humans
MH  - Male
MH  - Myocardial Revascularization/*methods
MH  - Prospective Studies
MH  - Risk Assessment
MH  - Risk Factors
MH  - *Stents
MH  - Treatment Outcome
EDAT- 2006/02/17 09:00
MHDA- 2006/03/22 09:00
CRDT- 2006/02/17 09:00
PHST- 2006/02/17 09:00 [pubmed]
PHST- 2006/03/22 09:00 [medline]
PHST- 2006/02/17 09:00 [entrez]
PST - ppublish
SO  - Conn Med. 2006 Jan;70(1):15-9.