PMID- 16483535
OWN - NLM
STAT- MEDLINE
DCOM- 20061114
LR  - 20161126
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1757
IP  - 8
DP  - 2006 Aug
TI  - Different types of biological proton transfer reactions studied by quantum 
      chemical methods.
PG  - 969-80
AB  - Different types of proton transfer occurring in biological systems are described 
      with examples mainly from ribonucleotide reductase (RNR) and cytochrome c oxidase 
      (CcO). Focus is put on situations where electron and proton transfer are rather 
      strongly coupled. In the long range radical transfer in RNR, it is shown that the 
      presence of hydrogen atom transfer (HAT) is the most logical explanation for the 
      experimental observations. In another example from RNR, it is shown that a 
      transition state for concerted motion of both proton and electron can be found 
      even if the donors are separated by a quite long distance. In CcO, the essential 
      proton transfer for the OO bond cleavage, and the most recent modelings of proton 
      translocation are described, indicating a few remaining major problems.
FAU - Blomberg, Margareta R A
AU  - Blomberg MR
AD  - Department of Physics, Stockholm Centre for Physics, Astronomy and Biotechnology 
      (SC-FAB), Stockholm University, Stockholm, Sweden. mb@physto.se
FAU - Siegbahn, Per E M
AU  - Siegbahn PE
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20060125
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (Protons)
RN  - EC 1.17.4.- (Ribonucleotide Reductases)
RN  - EC 1.9.3.1 (Electron Transport Complex IV)
SB  - IM
MH  - Biological Transport
MH  - Crystallography, X-Ray
MH  - Electron Transport Complex IV/chemistry/metabolism
MH  - Models, Molecular
MH  - Protein Conformation
MH  - *Protons
MH  - Quantum Theory
MH  - Ribonucleotide Reductases/chemistry/metabolism
RF  - 42
EDAT- 2006/02/18 09:00
MHDA- 2006/11/15 09:00
CRDT- 2006/02/18 09:00
PHST- 2005/11/15 00:00 [received]
PHST- 2005/12/20 00:00 [revised]
PHST- 2006/01/05 00:00 [accepted]
PHST- 2006/02/18 09:00 [pubmed]
PHST- 2006/11/15 09:00 [medline]
PHST- 2006/02/18 09:00 [entrez]
AID - S0005-2728(06)00003-X [pii]
AID - 10.1016/j.bbabio.2006.01.002 [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 2006 Aug;1757(8):969-80. doi: 10.1016/j.bbabio.2006.01.002. 
      Epub 2006 Jan 25.