PMID- 1649945
OWN - NLM
STAT- MEDLINE
DCOM- 19910826
LR  - 20190725
IS  - 0950-382X (Print)
IS  - 0950-382X (Linking)
VI  - 5
IP  - 4
DP  - 1991 Apr
TI  - Cell division and peptidoglycan assembly in Escherichia coli.
PG  - 791-5
AB  - Research on bacterial cell division has recently gained renewed impetus because 
      of new information about peptidoglycan assembly and about specific cell-division 
      genes and their products. This paper concerns aspects of cell division that 
      specifically concern the peptidoglycan. It is shown that upon division, 
      peptidoglycan assembly switches from lateral wall location to the cell centre, 
      that assembly takes place at the leading edge of the invaginating constriction, 
      that the mode of glycan strand insertion changes from a single-stranded mode to a 
      multi-stranded mode, and that the initiation of division (in contrast to its 
      continuation) requires penicillin-insensitive peptidoglycan synthesis (PIPS). A 
      membrane component X (possibly FtsQ) is proposed to coordinate PIPS with the cell 
      division-initiating protein FtsZ. It is suggested that a largely proteinaceous 
      macromolecular complex (divisome) at the leading edge of constriction encompasses 
      three compartments (cytoplasm, membrane and periplasm). The composition of this 
      complex is proposed to vary depending on whether division is being initiated or 
      completed.
FAU - Nanninga, N
AU  - Nanninga N
AD  - Department of Molecular Cell Biology, University of Amsterdam, The Netherlands.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Mol Microbiol
JT  - Molecular microbiology
JID - 8712028
RN  - 0 (Bacterial Proteins)
RN  - 0 (Escherichia coli Proteins)
RN  - 0 (FtsA protein, Bacteria)
RN  - 0 (FtsA protein, E coli)
RN  - 0 (Mucoproteins)
RN  - 0 (Penicillins)
RN  - 0 (Peptidoglycan)
RN  - 0 (Polysaccharides)
SB  - IM
GS  - FtsQ
GS  - FtsZ
MH  - Bacterial Proteins/metabolism
MH  - Cell Division/*physiology
MH  - Escherichia coli/*physiology
MH  - *Escherichia coli Proteins
MH  - Models, Biological
MH  - Mucoproteins/metabolism
MH  - Penicillins/pharmacology
MH  - Peptidoglycan/*biosynthesis/metabolism
MH  - Polysaccharides/metabolism
RF  - 48
EDAT- 1991/04/01 00:00
MHDA- 1991/04/01 00:01
CRDT- 1991/04/01 00:00
PHST- 1991/04/01 00:00 [pubmed]
PHST- 1991/04/01 00:01 [medline]
PHST- 1991/04/01 00:00 [entrez]
AID - 10.1111/j.1365-2958.1991.tb00751.x [doi]
PST - ppublish
SO  - Mol Microbiol. 1991 Apr;5(4):791-5. doi: 10.1111/j.1365-2958.1991.tb00751.x.