PMID- 1651044
OWN - NLM
STAT- MEDLINE
DCOM- 19910911
LR  - 20171006
IS  - 0386-300X (Print)
IS  - 0386-300X (Linking)
VI  - 45
IP  - 2
DP  - 1991 Apr
TI  - Neurovirulent strains of herpes simplex virus type 1 are not necessarily 
      competent for reactivatable latency.
PG  - 117-21
AB  - Ability of two neurovirulent strains (F and +GC (LPV) Miyama) of herpes simplex 
      virus type 1 (HSV-1) to establish and maintain reactivatable latency in 
      trigeminal ganglia (TG) was compared after intranasal inoculation of mice. The 
      +GC (LPV) Miyama strain showed a very low rate of virus reactivation in explant 
      cultures of TG, while the F strain showed a high rate of reactivation. These data 
      indicate that neurovirulent strains of HSV-1 are not always competent for 
      reactivatable latency, although most virulent strains of HSV-1 thus far reported 
      were competent for reactivatable latency.
FAU - Arao, Y
AU  - Arao Y
AD  - Department of Virology, Okayama University Medical School, Japan.
FAU - Hatano, A
AU  - Hatano A
FAU - Yamada, M
AU  - Yamada M
FAU - Uno, F
AU  - Uno F
FAU - Nii, S
AU  - Nii S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - Acta Med Okayama
JT  - Acta medica Okayama
JID - 0417611
SB  - IM
MH  - Administration, Intranasal
MH  - Animals
MH  - Mice
MH  - Mutation
MH  - Simplexvirus/genetics/*pathogenicity
MH  - Trigeminal Ganglion/*microbiology
MH  - Virulence/physiology
MH  - Virus Activation/*physiology
EDAT- 1991/04/01 00:00
MHDA- 1991/04/01 00:01
CRDT- 1991/04/01 00:00
PHST- 1991/04/01 00:00 [pubmed]
PHST- 1991/04/01 00:01 [medline]
PHST- 1991/04/01 00:00 [entrez]
AID - 10.18926/AMO/32190 [doi]
PST - ppublish
SO  - Acta Med Okayama. 1991 Apr;45(2):117-21. doi: 10.18926/AMO/32190.