PMID- 16511044
OWN - NLM
STAT- MEDLINE
DCOM- 20060602
LR  - 20190108
IS  - 1744-3091 (Electronic)
IS  - 1744-3091 (Linking)
VI  - 61
IP  - Pt 4
DP  - 2005 Apr 1
TI  - Purification, crystallization and preliminary X-ray diffraction analysis of the 
      human major histocompatibility antigen HLA-B*2703 complexed with a viral peptide 
      and with a self-peptide.
PG  - 372-4
AB  - The product of the human leukocyte antigen (HLA) gene HLA-B*2703 differs from 
      that of the prototypical subtype HLA-B*2705 by a single amino acid at heavy-chain 
      residue 59 that is involved in anchoring the peptide N-terminus within the A 
      pocket of the molecule. Two B*2703-peptide complexes were crystallized using the 
      hanging-drop vapour-diffusion method using PEG 8000 as a precipitant. The 
      crystals belong to space group P2(1) (pVIPR peptide) or P2(1)2(1)2(1) (pLMP2 
      peptide). Data sets were collected to 1.55 A (B*2703-pVIPR) or 2.0 A 
      (B*2703-pLMP2) resolution using synchrotron radiation. With B*2705-pVIPR as a 
      search model, a clear molecular-replacement solution was found for both B*2703 
      complexes.
FAU - Loll, Bernhard
AU  - Loll B
AD  - Institut fur Chemie/Kristallographie, Freie Universitat Berlin, Takustrasse 6, 
      14195 Berlin, Germany.
FAU - Zawacka, Anna
AU  - Zawacka A
FAU - Biesiadka, Jacek
AU  - Biesiadka J
FAU - Ruckert, Christine
AU  - Ruckert C
FAU - Volz, Armin
AU  - Volz A
FAU - Saenger, Wolfram
AU  - Saenger W
FAU - Uchanska-Ziegler, Barbara
AU  - Uchanska-Ziegler B
FAU - Ziegler, Andreas
AU  - Ziegler A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20050312
PL  - England
TA  - Acta Crystallogr Sect F Struct Biol Cryst Commun
JT  - Acta crystallographica. Section F, Structural biology and crystallization 
      communications
JID - 101226117
RN  - 0 (Antigen-Antibody Complex)
RN  - 0 (Antigens, Viral)
RN  - 0 (Autoantigens)
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-B*27:03 antigen)
RN  - 0 (HLA-B27 Antigen)
RN  - 0 (Peptide Fragments)
RN  - 0 (Viral Proteins)
SB  - IM
MH  - Antigen-Antibody Complex/*chemistry
MH  - Antigens, Viral/chemistry
MH  - Autoantigens/chemistry
MH  - Crystallization/methods
MH  - HLA-B Antigens/*chemistry/immunology
MH  - HLA-B27 Antigen
MH  - Humans
MH  - Peptide Fragments/chemistry/immunology
MH  - Viral Proteins/chemistry
MH  - Volatilization
MH  - X-Ray Diffraction
PMC - PMC1952442
EDAT- 2006/03/03 09:00
MHDA- 2006/06/03 09:00
PMCR- 2007/04/01
CRDT- 2006/03/03 09:00
PHST- 2005/01/23 00:00 [received]
PHST- 2005/03/08 00:00 [accepted]
PHST- 2006/03/03 09:00 [pubmed]
PHST- 2006/06/03 09:00 [medline]
PHST- 2006/03/03 09:00 [entrez]
PHST- 2007/04/01 00:00 [pmc-release]
AID - S1744309105007438 [pii]
AID - za5093 [pii]
AID - 10.1107/S1744309105007438 [doi]
PST - ppublish
SO  - Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Apr 1;61(Pt 4):372-4. doi: 
      10.1107/S1744309105007438. Epub 2005 Mar 12.