PMID- 16512809
OWN - NLM
STAT- MEDLINE
DCOM- 20060823
LR  - 20220410
IS  - 0105-4538 (Print)
IS  - 0105-4538 (Linking)
VI  - 61
IP  - 4
DP  - 2006 Apr
TI  - Pollen-food syndromes associated with weed pollinosis: an update from the 
      molecular point of view.
PG  - 461-76
AB  - Pollinosis patients often display adverse reactions upon the ingestion of 
      plant-derived foods as a result of immunoglobulin E (IgE) cross-reactive 
      structures shared by pollen and food allergen sources. The symptoms of such 
      pollen-food syndromes (PFS) or class 2 food allergies range from local oral 
      allergy syndrome to severe systemic anaphylaxis. Two clinical syndromes, the 
      celery-mugwort-spice syndrome and the mugwort-mustard-allergy syndrome have been 
      described in association with weed pollinosis. However, other associations 
      between weed pollinosis and hypersensitivity to certain kinds of food have also 
      been observed, like the mugwort-peach, the ragweed-melon-banana, the 
      plantain-melon, the pellitory-pistachio, the goosefoot-fruit, the Russian 
      thistle-saffron, and the hop-celery association. The number of allergen sources 
      involved, the allergens, and influencing factors including geography, diet, and 
      food preparation contribute to the high clinical complexity of PFS. So far, known 
      causative cross-reactive allergens include profilins, lipid transfer proteins, 
      and high-molecular weight allergens and/or glycoallergens. The current usage of 
      nonstandardized allergen extracts poses additional problems for both diagnosis 
      and therapy of PFS patients. Further identification and characterization of 
      involved allergens is inescapable for better understanding of PFS and vaccine 
      development. Panels of recombinant allergens and/or hypo-allergens are promising 
      tools to improve both PFS diagnostics and therapy.
FAU - Egger, M
AU  - Egger M
AD  - Department of Molecular Biology, Division of Allergy and Immunology, University 
      of Salzburg, Salzburg, Austria.
FAU - Mutschlechner, S
AU  - Mutschlechner S
FAU - Wopfner, N
AU  - Wopfner N
FAU - Gadermaier, G
AU  - Gadermaier G
FAU - Briza, P
AU  - Briza P
FAU - Ferreira, F
AU  - Ferreira F
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Denmark
TA  - Allergy
JT  - Allergy
JID - 7804028
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Allergens/*immunology
MH  - Ambrosia/*immunology
MH  - Cross Reactions
MH  - Food Hypersensitivity/diagnosis/etiology/*immunology/therapy
MH  - Humans
MH  - Immunoglobulin E/immunology
MH  - Plants, Edible/*immunology
MH  - Rhinitis, Allergic, Seasonal/*immunology
MH  - Syndrome
RF  - 132
EDAT- 2006/03/04 09:00
MHDA- 2006/08/24 09:00
CRDT- 2006/03/04 09:00
PHST- 2006/03/04 09:00 [pubmed]
PHST- 2006/08/24 09:00 [medline]
PHST- 2006/03/04 09:00 [entrez]
AID - ALL994 [pii]
AID - 10.1111/j.1398-9995.2006.00994.x [doi]
PST - ppublish
SO  - Allergy. 2006 Apr;61(4):461-76. doi: 10.1111/j.1398-9995.2006.00994.x.