PMID- 16521813
OWN - NLM
STAT- MEDLINE
DCOM- 20060324
LR  - 20190902
IS  - 0300-9173 (Print)
IS  - 0300-9173 (Linking)
VI  - 43
IP  - 1
DP  - 2006 Jan
TI  - [Potential and unsolved problems concerning caloric restriction in nutritional 
      therapeutics for the purpose of promoting health and controlling aging].
PG  - 89-91
AB  - Overeating and obesity are major health problems even in the elderly since they 
      lead to the metabolic syndrome, resulting in an increase in cardiovascular 
      disease. The development of novel nutritional therapeutics for the purpose of 
      promoting health and controlling ageing process aims at the self-helping elderly. 
      Caloric restriction (CR) has been widely investigated as a powerful method that 
      can prevent and reverse senescent changes. CR might counteract the deleterious 
      aspects of metabolic syndrome and may prolong lifespan even in humans. However, 
      we should keep in mind that several fundamental issues about CR still remain 
      unsolved. In addition, malnutrition and nutritional troubles are emerging 
      problems in the elderly in care. Thus, we emphasize that nutritional intervention 
      aiming at ageing control should be established and be developed as a custom-made 
      therapeutics for the elderly, who show great individual variation.
FAU - Shinmura, Ken
AU  - Shinmura K
AD  - Division of Geriatric Medicine, Department of Internal Medicine, Keio University 
      School of Medicine.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Nihon Ronen Igakkai Zasshi
JT  - Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics
JID - 7507332
SB  - IM
MH  - Aged
MH  - Aging/*physiology
MH  - *Caloric Restriction
MH  - Female
MH  - Health Promotion/*methods
MH  - Humans
MH  - Longevity
MH  - Male
MH  - Malnutrition/*prevention & control
MH  - Nutritional Physiological Phenomena
MH  - *Nutritional Support
EDAT- 2006/03/09 09:00
MHDA- 2006/03/25 09:00
CRDT- 2006/03/09 09:00
PHST- 2006/03/09 09:00 [pubmed]
PHST- 2006/03/25 09:00 [medline]
PHST- 2006/03/09 09:00 [entrez]
AID - 10.3143/geriatrics.43.89 [doi]
PST - ppublish
SO  - Nihon Ronen Igakkai Zasshi. 2006 Jan;43(1):89-91. doi: 10.3143/geriatrics.43.89.