PMID- 16535612
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20100625
LR  - 20210526
IS  - 0099-2240 (Print)
IS  - 1098-5336 (Electronic)
IS  - 0099-2240 (Linking)
VI  - 63
IP  - 5
DP  - 1997 May
TI  - Biodegradation of 2,4-Dichlorophenol through a Distal meta-Fission Pathway.
PG  - 2054-7
AB  - Alcaligenes eutrophus JMP222, a derivative of A. eutrophus JMP134 which has lost 
      plasmid pJP4 (encoding the tfd genes for the ortho fission pathway), was induced 
      for the meta fission pathway when grown on o-cresol. Resting cell suspensions, 
      grown on o-cresol, oxidized 2,4-dichlorophenol (2,4-DCP), a degradation product 
      of 2,4-dichlorophenoxyacetic acid, to 3,5-dichlorocatechol. Further degradation 
      of 3,5-dichlorocatechol was observed by the production of a yellow ring fission 
      product with liberation of chloride. Oxidation of 2,4-DCP (305 (mu)M) in 47 hs 
      resulted in 69% dehalogenation through this pathway. The ring fission product was 
      characterized as 2-hydroxy-3,5-dichloro-6-oxo-hexa-2,4-dienoic acid by gas 
      chromatography-mass spectrometry and gas chromatography-Fourier transform 
      infrared spectroscopy. These data indicate that 2,4-DCP is degraded through a 
      distal meta ring fission pathway, in contrast to either a suicidal proximal 
      fission or the standard ortho fission pathway.
FAU - Koh, S
AU  - Koh S
FAU - McCullar, M V
AU  - McCullar MV
FAU - Focht, D D
AU  - Focht DD
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Appl Environ Microbiol
JT  - Applied and environmental microbiology
JID - 7605801
PMC - PMC1389167
EDAT- 1997/05/01 00:00
MHDA- 1997/05/01 00:01
PMCR- 1997/05/01
CRDT- 1997/05/01 00:00
PHST- 1997/05/01 00:00 [pubmed]
PHST- 1997/05/01 00:01 [medline]
PHST- 1997/05/01 00:00 [entrez]
PHST- 1997/05/01 00:00 [pmc-release]
AID - 10.1128/aem.63.5.2054-2057.1997 [doi]
PST - ppublish
SO  - Appl Environ Microbiol. 1997 May;63(5):2054-7. doi: 
      10.1128/aem.63.5.2054-2057.1997.