PMID- 16542723 OWN - NLM STAT- MEDLINE DCOM- 20070928 LR - 20151119 IS - 0145-2126 (Print) IS - 0145-2126 (Linking) VI - 30 IP - 12 DP - 2006 Dec TI - Fludarabine-associated autoimmune hemolytic anemia occurring in B-cell chronic lymphocytic leukemia. PG - 1589-90 AB - Autoimmune phenomena are reported to occur frequently in B-cell chronic leukemia (B-CLL). Fludarabine, one of the most effective chemotherapeutic agents for CLL, may increase the risk of these phenomena and may be life-threatening. Here we present a case of an 80-year-old man with B-CLL who developed autoimmune hemolytic anemia (AIHA), associated with one cycle of fludarabine treatment, and who was successfully treated with rituximab and prednisolone. FAU - Nishida, Hiroko AU - Nishida H FAU - Murase, Tadashi AU - Murase T FAU - Ueno, Hironori AU - Ueno H FAU - Park, Jae Wong AU - Park JW FAU - Yano, Takahiro AU - Yano T FAU - Ikeda, Yasuo AU - Ikeda Y LA - eng PT - Case Reports PT - Letter DEP - 20060320 PL - England TA - Leuk Res JT - Leukemia research JID - 7706787 RN - 0 (Antibodies, Monoclonal) RN - 0 (Antibodies, Monoclonal, Murine-Derived) RN - 0 (Antineoplastic Agents) RN - 4F4X42SYQ6 (Rituximab) RN - 9PHQ9Y1OLM (Prednisolone) RN - FA2DM6879K (Vidarabine) RN - P2K93U8740 (fludarabine) SB - IM CIN - Leuk Res. 2007 Feb;31(2):267; author reply 268-9. PMID: 16716397 MH - Aged, 80 and over MH - Anemia, Hemolytic, Autoimmune/*complications/diagnosis/drug therapy MH - Antibodies, Monoclonal/administration & dosage MH - Antibodies, Monoclonal, Murine-Derived MH - Antineoplastic Agents/administration & dosage/*adverse effects MH - Disease Progression MH - Humans MH - Infusions, Intravenous MH - Leukemia, Lymphocytic, Chronic, B-Cell/*complications/diagnosis/drug therapy MH - Male MH - Prednisolone/administration & dosage MH - Remission Induction MH - Risk Factors MH - Rituximab MH - Treatment Outcome MH - Vidarabine/administration & dosage/adverse effects/*analogs & derivatives EDAT- 2006/03/18 09:00 MHDA- 2007/09/29 09:00 CRDT- 2006/03/18 09:00 PHST- 2006/02/07 00:00 [received] PHST- 2006/02/07 00:00 [revised] PHST- 2006/02/07 00:00 [accepted] PHST- 2006/03/18 09:00 [pubmed] PHST- 2007/09/29 09:00 [medline] PHST- 2006/03/18 09:00 [entrez] AID - S0145-2126(06)00069-5 [pii] AID - 10.1016/j.leukres.2006.02.011 [doi] PST - ppublish SO - Leuk Res. 2006 Dec;30(12):1589-90. doi: 10.1016/j.leukres.2006.02.011. Epub 2006 Mar 20.