PMID- 16573564
OWN - NLM
STAT- MEDLINE
DCOM- 20060511
LR  - 20221207
IS  - 0001-2815 (Print)
IS  - 0001-2815 (Linking)
VI  - 67
IP  - 3
DP  - 2006 Mar
TI  - Identification of a novel HLA-B*44 variant (B*4441) in three unrelated Caucasian 
      individuals.
PG  - 247-9
AB  - Here, we report the identification of a new human leukocyte antigen (HLA)-B*44 
      allele found almost simultaneous in three DNA samples which were part of routine 
      bone marrow donor typing by order of the German registry 'Aktion 
      Knochenmarkspende Bayern'. The samples appeared noticeable in different 
      polymerase chain reactions using sequence-specific primers (PCR-SSP) or 
      sequence-specific oligonucleotides (PCR-SSO). Sequence-based typing revealed a 
      novel allele officially designated as B*4441*. This sequence differs from 
      HLA-B*44020101/4427 by two nucleotide positions at the beginning of exon 3: by 
      position 353 (T to C) and by position 355 (A to C). These differences in sequence 
      result in deviant amino acids at codon 94 (Ile94Thr) and codon 95 (Ile95Leu).
FAU - Hoelsch, K
AU  - Hoelsch K
AD  - Laboratory for Medical Genetics, Dr Klein, Martinsried, Munich, Germany.
FAU - Lenggeler, I
AU  - Lenggeler I
FAU - Knabe, H
AU  - Knabe H
FAU - Hartel, K
AU  - Hartel K
FAU - Klein, H-G
AU  - Klein HG
FAU - Woelpl, A
AU  - Woelpl A
LA  - eng
PT  - Journal Article
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (Codon)
RN  - 0 (HLA-B Antigens)
SB  - IM
MH  - Adult
MH  - Alleles
MH  - Amino Acid Sequence
MH  - Amino Acid Substitution
MH  - Base Pairing
MH  - Base Sequence
MH  - Codon
MH  - Consensus Sequence
MH  - Exons
MH  - Female
MH  - Genetic Variation/*immunology
MH  - HLA-B Antigens/chemistry/*genetics/isolation & purification
MH  - Haplotypes
MH  - Humans
MH  - Introns
MH  - Male
MH  - Molecular Sequence Data
MH  - Polymerase Chain Reaction
MH  - Sequence Analysis, DNA
MH  - White People/*genetics
EDAT- 2006/04/01 09:00
MHDA- 2006/05/12 09:00
CRDT- 2006/04/01 09:00
PHST- 2006/04/01 09:00 [pubmed]
PHST- 2006/05/12 09:00 [medline]
PHST- 2006/04/01 09:00 [entrez]
AID - TAN563 [pii]
AID - 10.1111/j.1399-0039.2006.00563.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2006 Mar;67(3):247-9. doi: 10.1111/j.1399-0039.2006.00563.x.