PMID- 16610248 OWN - NLM STAT- MEDLINE DCOM- 20060605 LR - 20220113 IS - 0391-4097 (Print) IS - 0391-4097 (Linking) VI - 29 IP - 2 DP - 2006 Feb TI - Association of pelvic endometriosis with alopecia universalis, autoimmune thyroiditis and multiple sclerosis. PG - 182-9 AB - An adult Caucasian female developed a previously unreported association of pelvic endometriosis (PE) with the triad of alopecia universalis (AU), autoimmune thyroiditis (AT) and multiple sclerosis (MS). Molecular human leukocyte antigen (HLA)-tissue typing of this subject showed the presence of the DR(2) 15 and DR(3) 17 alleles, which are associated to an increased risk of MS and AT, respectively. Clinical onset of AT followed withdrawal of corticosteroid treatment for AU, whereas MS become clinically evident after withdrawal from long-term estroprogestin therapy for PE. This clinical case is presented to discuss the autoimmune origin of PE, its possible association with multiple autoimmune disorders as well as the effect of other factors, such as administration and/ or discontinuation of specific hormonal regimens, on genetic autoimmunity-prone background. FAU - Alviggi, C AU - Alviggi C AD - Department of Gynecological, Obstetric, and Urological Sciences and Medicine of Reproduction, Institute of Experimental Endocrinology and Oncology, National Research Council (IEOS-CNR), Napoli, Italy. FAU - Carrieri, P B AU - Carrieri PB FAU - Pivonello, R AU - Pivonello R FAU - Scarano, V AU - Scarano V FAU - Pezzella, M AU - Pezzella M FAU - De Placido, G AU - De Placido G FAU - Colao, A AU - Colao A FAU - Matarese, G AU - Matarese G LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Italy TA - J Endocrinol Invest JT - Journal of endocrinological investigation JID - 7806594 RN - 0 (Autoantibodies) RN - 0 (Hormones) SB - IM MH - Adolescent MH - Alopecia/*complications MH - Autoantibodies/blood MH - Endometriosis/*complications/*immunology MH - Female MH - Hormones/adverse effects/blood/therapeutic use MH - Humans MH - Multiple Sclerosis/*complications/genetics MH - Thyroiditis, Autoimmune/*complications/genetics EDAT- 2006/04/14 09:00 MHDA- 2006/06/06 09:00 CRDT- 2006/04/14 09:00 PHST- 2006/04/14 09:00 [pubmed] PHST- 2006/06/06 09:00 [medline] PHST- 2006/04/14 09:00 [entrez] AID - 1185 [pii] AID - 10.1007/BF03344095 [doi] PST - ppublish SO - J Endocrinol Invest. 2006 Feb;29(2):182-9. doi: 10.1007/BF03344095.