PMID- 16617974
OWN - NLM
STAT- MEDLINE
DCOM- 20060531
LR  - 20061115
IS  - 0005-2086 (Print)
IS  - 0005-2086 (Linking)
VI  - 50
IP  - 1
DP  - 2006 Mar
TI  - Campylobacter jejuni strains of human and chicken origin are invasive in chickens 
      after oral challenge.
PG  - 10-4
AB  - The aim of the study was to evaluate the colonizing ability and the invasive 
      capacity of selected Campylobacter jejuni strains of importance for the 
      epidemiology of C jejuni in Danish broiler chickens. Four C. jejuni strains were 
      selected for experimental colonization studies in day-old and 14-day-old chickens 
      hatched from specific pathogen free (SPF) eggs. Of the four C. jejuni strains 
      tested, three were Penner heat-stable serotype 2, flaA type 1/1, the most common 
      type found among broilers and human cases in Denmark. The fourth strain was 
      Penner heat-stable serotype 19, which has been shown to be associated with the 
      Guillain Barre Syndrome (GBS) in humans. The minimum dose for establishing 
      colonization in the day-old chickens was approximately 2 cfu, whereas two- to 
      threefold higher doses were required for establishing colonization in the 
      14-day-old chickens. Two of the C. jejuni strains were shown to be invasive in 
      orally challenged chickens as well as in three different human epithelial cell 
      lines.
FAU - Knudsen, Katrine Norrelund
AU  - Knudsen KN
AD  - Department of Poultry, Fish and Fur Animals, Danish Institute for Food and 
      Veterinary Research, Hangovej 2, DK-8200 Aarhus N, Denmark.
FAU - Bang, Dang Duong
AU  - Bang DD
FAU - Andresen, Lars Ole
AU  - Andresen LO
FAU - Madsen, Mogens
AU  - Madsen M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Avian Dis
JT  - Avian diseases
JID - 0370617
SB  - IM
MH  - Animals
MH  - Caco-2 Cells
MH  - Campylobacter Infections/microbiology/transmission/*veterinary
MH  - Campylobacter jejuni/isolation & purification/pathogenicity/*physiology
MH  - Cell Line
MH  - Chickens/*microbiology
MH  - HeLa Cells
MH  - Humans
MH  - Poultry Diseases/*microbiology
MH  - Specific Pathogen-Free Organisms
EDAT- 2006/04/19 09:00
MHDA- 2006/06/01 09:00
CRDT- 2006/04/19 09:00
PHST- 2006/04/19 09:00 [pubmed]
PHST- 2006/06/01 09:00 [medline]
PHST- 2006/04/19 09:00 [entrez]
AID - 10.1637/7376-051005R.1 [doi]
PST - ppublish
SO  - Avian Dis. 2006 Mar;50(1):10-4. doi: 10.1637/7376-051005R.1.