PMID- 16626841
OWN - NLM
STAT- MEDLINE
DCOM- 20061031
LR  - 20131121
IS  - 0278-5846 (Print)
IS  - 0278-5846 (Linking)
VI  - 30
IP  - 7
DP  - 2006 Sep 30
TI  - Plasma levels of brain derived-neurotrophic factor and catecholamine metabolites 
      are increased during active phase of psychotic symptoms in CNS lupus: a case 
      report.
PG  - 1359-63
AB  - In the present study, the authors reported a case of systemic lupus erythematosus 
      (SLE) with central nervous system involvement (CNS lupus). The authors also 
      longitudinally investigated plasma levels of brain-derived neurotrophic factor 
      (BDNF) and catecholamine metabolites in the patient, and found that plasma levels 
      of BDNF, 3-methoxy-4-hydroxyphenylglycol (MHPG), and homovanillic acid (HVA) were 
      raised in accordance with the severity of psychotic symptoms in this case of CNS 
      lupus. These results suggest that it is useful to measure plasma levels of BDNF 
      and the catecholamine metabolites in order to predict the severity of psychotic 
      symptoms in CNS lupus and to provide a differential diagnosis from that of 
      steroid-induced psychosis.
FAU - Ikenouchi, Atsuko
AU  - Ikenouchi A
AD  - Department of Psychiatry, University of Occupational and Environmental Health, 
      Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka 8078555, Japan.
FAU - Yoshimura, Reiji
AU  - Yoshimura R
FAU - Ikemura, Naomi
AU  - Ikemura N
FAU - Utsunomiya, Kensuke
AU  - Utsunomiya K
FAU - Mitoma, Masae
AU  - Mitoma M
FAU - Nakamura, Jun
AU  - Nakamura J
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20060419
PL  - England
TA  - Prog Neuropsychopharmacol Biol Psychiatry
JT  - Progress in neuro-psychopharmacology & biological psychiatry
JID - 8211617
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 0 (Catecholamines)
RN  - 0 (Immunosuppressive Agents)
RN  - 534-82-7 (Methoxyhydroxyphenylglycol)
RN  - X77S6GMS36 (Homovanillic Acid)
SB  - IM
MH  - Adult
MH  - Brain-Derived Neurotrophic Factor/*blood
MH  - Catecholamines/*blood
MH  - Homovanillic Acid/blood
MH  - Humans
MH  - Immunosuppressive Agents/therapeutic use
MH  - Lupus Erythematosus, Systemic/*blood/complications/drug therapy/pathology
MH  - Magnetic Resonance Imaging/methods
MH  - Methoxyhydroxyphenylglycol/blood
MH  - Psychotic Disorders/*blood/complications/drug therapy/pathology
MH  - Tomography, Emission-Computed, Single-Photon/methods
EDAT- 2006/04/22 09:00
MHDA- 2006/11/01 09:00
CRDT- 2006/04/22 09:00
PHST- 2006/04/22 09:00 [pubmed]
PHST- 2006/11/01 09:00 [medline]
PHST- 2006/04/22 09:00 [entrez]
AID - S0278-5846(06)00079-0 [pii]
AID - 10.1016/j.pnpbp.2006.03.006 [doi]
PST - ppublish
SO  - Prog Neuropsychopharmacol Biol Psychiatry. 2006 Sep 30;30(7):1359-63. doi: 
      10.1016/j.pnpbp.2006.03.006. Epub 2006 Apr 19.