PMID- 16626957
OWN - NLM
STAT- MEDLINE
DCOM- 20070306
LR  - 20131121
IS  - 0955-2863 (Print)
IS  - 0955-2863 (Linking)
VI  - 18
IP  - 1
DP  - 2007 Jan
TI  - Soy protein with and without isoflavones fails to substantially increase 
      postprandial antioxidant capacity.
PG  - 46-53
AB  - Five methods for the assessment of antioxidant capacity [whole plasma conjugated 
      diene formation, low-density lipoprotein oxidation susceptibility, 
      ferric-reducing ability of plasma, oxygen radical absorbance capacity and 
      perchloric-acid-treated oxygen radical absorbance capacity (PCA-ORAC)] were used 
      in a randomized, double blind, crossover study to determine the acute 
      postprandial antioxidant protection imparted by the isoflavone component of soy. 
      On separate days, 16 subjects consumed one of three isocaloric shakes containing 
      25 g of protein in the form of soy, with 107 mg of total aglycone units of 
      isoflavones, soy with trace isoflavones (<4 mg) or total milk protein. Blood was 
      collected at baseline, 4 h, 6 h and 8 h after consumption. Antioxidant capacity, 
      serum isoflavone levels, fat-soluble antioxidants and plasma vitamin C levels 
      were evaluated. Repeated measures analysis of variance showed no significant 
      differences (P=.05) within treatments over time in four of five antioxidant 
      capacity measurements. Significant differences over time between the soy with 
      trace isoflavones and the total milk protein group were observed using the 
      PCA-ORAC assay. It can be concluded that, on an acute basis, a significant 
      increase in serum antioxidant capacity is not detectable following consumption of 
      soy protein.
FAU - Heneman, Karrie M
AU  - Heneman KM
AD  - Department of Nutrition, University of California, Davis, CA 95616-8669, USA.
FAU - Chang, Hebron C
AU  - Chang HC
FAU - Prior, Ronald L
AU  - Prior RL
FAU - Steinberg, Francene M
AU  - Steinberg FM
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20060419
PL  - United States
TA  - J Nutr Biochem
JT  - The Journal of nutritional biochemistry
JID - 9010081
RN  - 0 (Antioxidants)
RN  - 0 (Dietary Proteins)
RN  - 0 (Ferric Compounds)
RN  - 0 (Isoflavones)
RN  - 0 (Lipoproteins, LDL)
RN  - 0 (Reactive Oxygen Species)
RN  - 0 (Soybean Proteins)
RN  - 6287WC5J2L (daidzein)
RN  - DH2M523P0H (Genistein)
RN  - PQ6CK8PD0R (Ascorbic Acid)
SB  - IM
MH  - Antioxidants/*analysis/pharmacology
MH  - Ascorbic Acid/blood
MH  - Cross-Over Studies
MH  - Dietary Proteins/*administration & dosage
MH  - Double-Blind Method
MH  - Female
MH  - Ferric Compounds/chemistry
MH  - *Food
MH  - Genistein/blood
MH  - Humans
MH  - Isoflavones/*administration & dosage/blood
MH  - Lipid Peroxidation
MH  - Lipoproteins, LDL/chemistry
MH  - Male
MH  - Oxidation-Reduction
MH  - Reactive Oxygen Species/chemistry
MH  - Soybean Proteins/*administration & dosage
EDAT- 2006/04/22 09:00
MHDA- 2007/03/07 09:00
CRDT- 2006/04/22 09:00
PHST- 2005/11/03 00:00 [received]
PHST- 2006/03/02 00:00 [revised]
PHST- 2006/03/06 00:00 [accepted]
PHST- 2006/04/22 09:00 [pubmed]
PHST- 2007/03/07 09:00 [medline]
PHST- 2006/04/22 09:00 [entrez]
AID - S0955-2863(06)00068-4 [pii]
AID - 10.1016/j.jnutbio.2006.03.001 [doi]
PST - ppublish
SO  - J Nutr Biochem. 2007 Jan;18(1):46-53. doi: 10.1016/j.jnutbio.2006.03.001. Epub 
      2006 Apr 19.