PMID- 16632237
OWN - NLM
STAT- MEDLINE
DCOM- 20061106
LR  - 20220409
IS  - 1056-8727 (Print)
IS  - 1056-8727 (Linking)
VI  - 20
IP  - 3
DP  - 2006 May-Jun
TI  - The influence of ethnicity on health-related quality of life in diabetes 
      mellitus: a population-based, multiethnic study.
PG  - 170-8
AB  - OBJECTIVES: The aims of this study were to evaluate the influence of ethnicity on 
      health-related quality of life (HRQoL) in diabetic participants using both 
      profile [the Short-Form 36 (SF-36)] and single-index (the SF-6D) instruments and 
      to evaluate the usefulness of the SF-6D as a summary measure for the SF-36. 
      RESEARCH DESIGN AND METHODS: Using data from a cross-sectional, population-based 
      survey of Chinese, Malay, and Indians in Singapore, we analyzed the influence of 
      ethnicity and other variables on each SF-36 scale and SF-6D scores using linear 
      regression models to adjust for the influence of known determinants of HRQoL. 
      RESULTS: Data from 309 diabetic respondents were analyzed. Compared with other 
      ethnicities, Indians were most likely to report impaired HRQoL. The unadjusted 
      influence of ethnicity on HRQoL exceeded the minimum clinically important 
      difference (MCID) for all SF-36 scales (MCID: 5 points) and the SF-6D (MCID: 
      0.033 points). After adjusting for gender, age, and education, the influence of 
      Chinese ethnicity exceeded the MCID for all SF-36 scales, except vitality (VT) 
      and mental health (MH), as well as for the SF-6D. The influence of Malay 
      ethnicity exceeded the MCID only for the SF-36 MH scale and the SF-6D. The 
      influence of ethnicity on HRQoL persisted after adjusting further for other 
      determinants of HRQoL. The SF-6D reflected the ethnic trends for some but not all 
      SF-36 scales. CONCLUSIONS: After adjusting for demographic, socioeconomic, and 
      other factors known to influence HRQoL, ethnicity remained an important factor 
      influencing HRQoL in this population-based multiethnic sample of diabetic Asians. 
      Further studies to identify modifiable factors explaining the ethnic disparities 
      in HRQoL among diabetic participants are needed. The SF-6D may be a useful 
      summary measure for the SF-36.
FAU - Wee, Hwee-Lin
AU  - Wee HL
AD  - Department of Pharmacy, National University of Singapore, and Department of 
      Rheumatology and Immunology, Singapore General Hospital, Singapore, Republic of 
      Singapore.
FAU - Li, Shu-Chuen
AU  - Li SC
FAU - Cheung, Yin-Bun
AU  - Cheung YB
FAU - Fong, Kok-Yong
AU  - Fong KY
FAU - Thumboo, Julian
AU  - Thumboo J
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Diabetes Complications
JT  - Journal of diabetes and its complications
JID - 9204583
SB  - IM
MH  - Adult
MH  - Aged
MH  - China/ethnology
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus/*ethnology/psychology
MH  - Female
MH  - *Health Status Indicators
MH  - Humans
MH  - India/ethnology
MH  - Malaysia/ethnology
MH  - Male
MH  - Middle Aged
MH  - Population Groups/ethnology/statistics & numerical data
MH  - *Quality of Life
MH  - Singapore
MH  - Social Class
EDAT- 2006/04/25 09:00
MHDA- 2006/11/07 09:00
CRDT- 2006/04/25 09:00
PHST- 2004/12/23 00:00 [received]
PHST- 2005/06/07 00:00 [revised]
PHST- 2005/06/22 00:00 [accepted]
PHST- 2006/04/25 09:00 [pubmed]
PHST- 2006/11/07 09:00 [medline]
PHST- 2006/04/25 09:00 [entrez]
AID - S1056-8727(05)00079-6 [pii]
AID - 10.1016/j.jdiacomp.2005.06.010 [doi]
PST - ppublish
SO  - J Diabetes Complications. 2006 May-Jun;20(3):170-8. doi: 
      10.1016/j.jdiacomp.2005.06.010.