PMID- 16640706
OWN - NLM
STAT- MEDLINE
DCOM- 20061003
LR  - 20161128
IS  - 0742-2822 (Print)
IS  - 0742-2822 (Linking)
VI  - 23
IP  - 4
DP  - 2006 Apr
TI  - Maximum longitudinal relaxation velocity of the left ventricle: its clinical 
      value and relationship with NT-proBNP plasma levels in heart failure.
PG  - 295-302
AB  - BACKGROUND: M-mode recordings of the mitral annulus to measure the maximum 
      ascending velocity during early diastole as an expression of maximum longitudinal 
      relaxation velocity of the left ventricle (RVm) can be used as an index of left 
      ventricular (LV) diastolic function. The purpose of this study was to determine 
      the relationship of RVm with LV functional parameters in patients with heart 
      failure, with N-terminal pro-brain natriuretic peptide (NT-proBNP) plasma levels, 
      and with their functional classification. METHODS AND RESULTS: RVm was recorded 
      in 97 patients by M-mode echocardiography. Patients were classified according to 
      the New York Heart Association (NYHA) and the concentration of NT-proBNP was 
      determined. Patients with ejection fraction (EF)>40 showed a significant 
      correlation between RVm and mitral annulus motion (MAM), mitral flow propagation 
      velocity, E/A, age, deceleration time (DT), and NT-proBNP. In patients with 
      EF<or=40, RVm correlated significantly with MAM, EF, and NT-proBNP. RVm values 
      were higher in NYHA class I compared to II and III, P<0.0001. CONCLUSIONS: RVm 
      correlates better with functional parameters in patients with EF>40, though its 
      relationship with NT-proBNP both in patients with EF>or<or=40 is to be 
      highlighted. Correlation between RVm and NT-proBNP is influenced by age, EF, and 
      E/A, whereas in patients with EF>40 it is influenced only by age. RVm values 
      showed a significant decrease in NYHA class II and III.
FAU - Talens-Visconti, Raquel
AU  - Talens-Visconti R
AD  - Research Center La Fe Hospital, Valencia, Spain.
FAU - Rivera, Miguel
AU  - Rivera M
FAU - Climent, Vicente
AU  - Climent V
FAU - Valero, Ricardo
AU  - Valero R
FAU - Martinez-Dolz, Luis
AU  - Martinez-Dolz L
FAU - Sancho-Tello, Ma Jose
AU  - Sancho-Tello MJ
FAU - Cortes, Raquel
AU  - Cortes R
FAU - Miro, Vicente
AU  - Miro V
FAU - Sevilla, Begona
AU  - Sevilla B
FAU - Perez-Bosca, Jose Leandro
AU  - Perez-Bosca JL
FAU - Bertomeu, Vicente
AU  - Bertomeu V
FAU - Salvador, Antonio
AU  - Salvador A
FAU - Jordan, Alejandro
AU  - Jordan A
FAU - Marin, Francisco
AU  - Marin F
FAU - Sogorb, Francisco
AU  - Sogorb F
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Echocardiography
JT  - Echocardiography (Mount Kisco, N.Y.)
JID - 8511187
RN  - 0 (Biomarkers)
RN  - 0 (Peptide Fragments)
RN  - 0 (pro-brain natriuretic peptide (1-76))
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
MH  - Aged
MH  - Biomarkers
MH  - Echocardiography, Doppler
MH  - Female
MH  - Heart Failure/blood/diagnostic imaging/*physiopathology
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Mitral Valve/diagnostic imaging/*physiopathology
MH  - Multivariate Analysis
MH  - Natriuretic Peptide, Brain/*blood
MH  - Observer Variation
MH  - Peptide Fragments/*blood
MH  - Stroke Volume/*physiology
MH  - Ventricular Function, Left/*physiology
EDAT- 2006/04/28 09:00
MHDA- 2006/10/04 09:00
CRDT- 2006/04/28 09:00
PHST- 2006/04/28 09:00 [pubmed]
PHST- 2006/10/04 09:00 [medline]
PHST- 2006/04/28 09:00 [entrez]
AID - ECHO205 [pii]
AID - 10.1111/j.1540-8175.2006.00205.x [doi]
PST - ppublish
SO  - Echocardiography. 2006 Apr;23(4):295-302. doi: 10.1111/j.1540-8175.2006.00205.x.