PMID- 16676702
OWN - NLM
STAT- MEDLINE
DCOM- 20060608
LR  - 20191109
IS  - 1526-484X (Print)
IS  - 1526-484X (Linking)
VI  - 16
IP  - 1
DP  - 2006 Feb
TI  - Carbohydrate influences plasma interleukin-6 but not C-reactive protein or 
      creatine kinase following a 32-km mountain trail race.
PG  - 36-46
AB  - Attenuation of exercise-induced interleukin-6 (IL-6) responses by carbohydrate 
      (CHO) has been demonstrated in studies comparing controlled doses (> or = 0.9 g x 
      kg(-1) x h(-1)) to placebo, but not in studies of voluntary intake. This study 
      sought to determine if attenuation of the IL-6 response during a 32.2-km mountain 
      trail race occurs for high compared to low ad libitum CHO intakes. IL-6, 
      C-reactive protein (CRP), and creatine kinase activity (CK) were analyzed from 
      blood samples collected 12 h pre-, 0, 4, and 24 h post-race. Subjects were 
      grouped into low (n =14, 0.4 +/- 0.1 g x kg(-1) x h(-1)) and high (n =18, 0.8 +/- 
      0.2 g x kg(-1) x h(-1)) CHO intake groups. IL-6 0 h post-race (P < 0.05) was 
      higher in the low (40.2 +/- 22.7 pg x mL(-1)) compared to the high CHO group 
      (32.7 +/- 22.1 pg x mL(-1)). CRP and CK both increased post-race, but no 
      differences were observed between groups. Attenuation of exercise-induced IL-6 is 
      apparent across a range of CHO intakes.
FAU - Miles, Mary P
AU  - Miles MP
AD  - Dept of Health and Human Development, Montana State University, Bozeman 59717, 
      USA.
FAU - Walker, Erin E
AU  - Walker EE
FAU - Conant, Stephen B
AU  - Conant SB
FAU - Hogan, Shelly P
AU  - Hogan SP
FAU - Kidd, Jessy R
AU  - Kidd JR
LA  - eng
GR  - P20 RR-16455-03/RR/NCRR NIH HHS/United States
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Interleukin-6)
RN  - 9007-41-4 (C-Reactive Protein)
RN  - EC 2.7.3.2 (Creatine Kinase)
SB  - IM
MH  - Adult
MH  - Analysis of Variance
MH  - C-Reactive Protein/*drug effects
MH  - Creatine Kinase/*blood/*drug effects
MH  - Dietary Carbohydrates/blood/*pharmacology
MH  - Exercise/physiology
MH  - Female
MH  - Humans
MH  - Interleukin-6/*blood
MH  - Male
MH  - *Running
MH  - Time Factors
EDAT- 2006/05/09 09:00
MHDA- 2006/06/09 09:00
CRDT- 2006/05/09 09:00
PHST- 2006/05/09 09:00 [pubmed]
PHST- 2006/06/09 09:00 [medline]
PHST- 2006/05/09 09:00 [entrez]
AID - 10.1123/ijsnem.16.1.36 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2006 Feb;16(1):36-46. doi: 10.1123/ijsnem.16.1.36.