PMID- 16686301
OWN - NLM
STAT- MEDLINE
DCOM- 20060630
LR  - 20181201
IS  - 1197-8554 (Print)
IS  - 1197-8554 (Linking)
VI  - 21
DP  - 2005
TI  - Home peritoneal ultrafiltration in patients with severe congestive heart failure 
      without end-stage renal disease.
PG  - 123-7
AB  - Congestive heart failure (CHF), mainly because of ischemic heart disease, is 
      becoming a common medical problem. As CHF worsens and reaches New York Heart 
      Association (NYHA) class IV, many patients can become refractory to medical 
      therapy, especially those who are elderly or who have pre-existing non uremic 
      chronic renal failure. For such patients, quality of life, morbidity, and 
      mortality are expected to be bad. Our objective in the present study was to make 
      a preliminary assessment of the usefulness of icodextrin administered in a single 
      nocturnal peritoneal exchange to patients nonrespondent to the maximal 
      conventional medical therapy. We studied two patients (aged 80 and 87 years), who 
      were affected by severe dilatative cardiomyopathy and moderate-to-severe chronic 
      renal failure. After at least 12 months of treatment, we observed a significant 
      improvement in quality of life and a reduction in morbidity and hospitalization 
      in both patients. Both patients also significantly increased their creatinine 
      clearance. One patient maintained ejection fraction stability (22%-->27%); the 
      other experienced an increase in ejection fraction to 50%from 25%. These 
      preliminary observations suggest that a single nocturnal exchange with icodextrin 
      can be an effective treatment in patients affected by refractory CHF and 
      moderate-to-severe chronic renal failure.
FAU - Bertoli, Silvio V
AU  - Bertoli SV
AD  - Renal Unit, Policlinico MultiMedica, Sesto San Giovanni, Milan, Italy. 
      silvio.bertoli@multimedica.it
FAU - Ciurlino, Daniele
AU  - Ciurlino D
FAU - Maccario, Massimo
AU  - Maccario M
FAU - Martino, Stefania
AU  - Martino S
FAU - Bigatti, Giada
AU  - Bigatti G
FAU - Traversi, Lara
AU  - Traversi L
FAU - Procaccio, Mirella
AU  - Procaccio M
FAU - Buzzi, Laura
AU  - Buzzi L
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Canada
TA  - Adv Perit Dial
JT  - Advances in peritoneal dialysis. Conference on Peritoneal Dialysis
JID - 9104803
RN  - 0 (Glucans)
RN  - 0 (Hemodialysis Solutions)
RN  - 2NX48Z0A9G (Icodextrin)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Aged, 80 and over
MH  - Cardiomyopathy, Dilated/complications
MH  - Female
MH  - Glucans/therapeutic use
MH  - Glucose/therapeutic use
MH  - Heart Failure/complications/physiopathology/*therapy
MH  - Hemodialysis Solutions
MH  - *Hemodialysis, Home
MH  - Humans
MH  - Icodextrin
MH  - Kidney Failure, Chronic/complications
MH  - Male
MH  - *Peritoneal Dialysis
MH  - Ultrafiltration
EDAT- 2006/05/12 09:00
MHDA- 2006/07/01 09:00
CRDT- 2006/05/12 09:00
PHST- 2006/05/12 09:00 [pubmed]
PHST- 2006/07/01 09:00 [medline]
PHST- 2006/05/12 09:00 [entrez]
PST - ppublish
SO  - Adv Perit Dial. 2005;21:123-7.