PMID- 16688658
OWN - NLM
STAT- MEDLINE
DCOM- 20061012
LR  - 20131121
IS  - 0044-2771 (Print)
IS  - 0044-2771 (Linking)
VI  - 44
IP  - 5
DP  - 2006 May
TI  - [Symptom- versus endoscopy-based diagnosis and treatment of gastroesophageal 
      reflux disease (GERD)].
PG  - 399-410
AB  - The current guidelines of the German Society for Digestive Diseases (DGVS) 
      endoscopy recommends for patients representing with reflux symptoms. In daily 
      routine as well as in Guidelines from other countries and international 
      guidelines, however, a symptom-based strategy for the management of patients with 
      reflux disease is favoured. Since either strategies is dependent on specific 
      clinical findings, neither can be recommended. The preference for one or the 
      other strategy depends on the prevalence of so-called alarm symptoms, risk 
      factors for a reflux carcinoma or Barrett's metaplasia, demographic factors, e. 
      g., age and gender, patient's wish and initial response to empirical therapy with 
      proton pump inhibitors (PPI). However, most patients with characteristic reflux 
      symptoms without any alarm symptoms and/or other risk factors can be safely 
      managed with a symptom-based strategy in acute and long-term care.
FAU - Morgner-Miehlke, A
AU  - Morgner-Miehlke A
AD  - Medizinische Klinik I, Universitatsklinikum Carl Gustav Carus Dresden.
FAU - Koop, H
AU  - Koop H
FAU - Blum, A L
AU  - Blum AL
FAU - Hermans, M-L
AU  - Hermans ML
FAU - Miehlke, S
AU  - Miehlke S
FAU - Labenz, J
AU  - Labenz J
LA  - ger
PT  - English Abstract
PT  - Journal Article
TT  - Abklarung und Therapie von Refluxbeschwerden.
PL  - Germany
TA  - Z Gastroenterol
JT  - Zeitschrift fur Gastroenterologie
JID - 0033370
RN  - 0 (Anti-Ulcer Agents)
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Adenocarcinoma/diagnosis
MH  - Anti-Ulcer Agents/therapeutic use
MH  - Barrett Esophagus/diagnosis
MH  - Diagnosis, Differential
MH  - Disease Progression
MH  - *Endoscopy, Digestive System
MH  - Esophageal Neoplasms/diagnosis
MH  - Esophagitis, Peptic/complications/*diagnosis/drug therapy
MH  - Gastroesophageal Reflux/complications/*diagnosis/drug therapy
MH  - Humans
MH  - Long-Term Care
MH  - *Practice Guidelines as Topic
MH  - Proton Pump Inhibitors
MH  - Risk Factors
MH  - Treatment Outcome
EDAT- 2006/05/12 09:00
MHDA- 2006/10/13 09:00
CRDT- 2006/05/12 09:00
PHST- 2006/05/12 09:00 [pubmed]
PHST- 2006/10/13 09:00 [medline]
PHST- 2006/05/12 09:00 [entrez]
AID - 10.1055/s-2006-926619 [doi]
PST - ppublish
SO  - Z Gastroenterol. 2006 May;44(5):399-410. doi: 10.1055/s-2006-926619.