PMID- 16689019
OWN - NLM
STAT- MEDLINE
DCOM- 20060720
LR  - 20220317
IS  - 0920-5063 (Print)
IS  - 0920-5063 (Linking)
VI  - 17
IP  - 3
DP  - 2006
TI  - Hydrophilic interpenetrating polymer networks of poly(dimethyl siloxane) (PDMS) 
      as biomaterial for cochlear implants.
PG  - 341-55
AB  - Poly(dimethyl siloxane) (PDMS) was bulk-modified to develop a new intra-cochlear 
      electrode that can closely hug the inner wall of scala tympani (ST). The 
      hydrophilicity of bulk and surface of PDMS was changed using a sequential method 
      for preparation of interpenetrating polymer networks (IPNs). A series of IPNs, 
      based on PDMS and poly(acrylic acid) (PAAc), was synthesized and characterized by 
      means of attenuated total reflectance Fourier transform infrared spectroscopy, 
      water contact-angle measurement, dynamic mechanical thermal analysis and peel 
      strength tests. The performances of actual-sized fabricated electrodes were 
      assessed inside a transparent model of ST, which was filled with saline. The cell 
      behavior of L929 fibroblasts on materials was studied in vitro.
FAU - Abbasi, F
AU  - Abbasi F
AD  - Research Centerfor Polymeric Materials, Sahand University of Technology, Tabriz, 
      Iran. f.abbasi@sut.ac.ir
FAU - Mirzadeh, H
AU  - Mirzadeh H
FAU - Simjoo, M
AU  - Simjoo M
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Biomater Sci Polym Ed
JT  - Journal of biomaterials science. Polymer edition
JID - 9007393
RN  - 0 (Acrylic Resins)
RN  - 0 (Biocompatible Materials)
RN  - 0 (Dimethylpolysiloxanes)
RN  - 0 (Nylons)
RN  - 0 (Silicones)
RN  - 0 (poly(dimethylsiloxane)-polyamide copolymer)
RN  - 059QF0KO0R (Water)
RN  - 25852-47-5 (Hydrogel, Polyethylene Glycol Dimethacrylate)
RN  - 4Q93RCW27E (carbopol 940)
SB  - IM
MH  - Acrylic Resins/chemistry
MH  - Animals
MH  - Biocompatible Materials/*chemistry
MH  - Cell Adhesion
MH  - Cells, Cultured
MH  - *Cochlear Implants
MH  - Dimethylpolysiloxanes/*chemistry
MH  - Electrodes
MH  - Fibroblasts
MH  - Hydrogel, Polyethylene Glycol Dimethacrylate/chemistry
MH  - Materials Testing
MH  - Mice
MH  - Nylons/*chemistry
MH  - Silicones/chemistry
MH  - Water/chemistry/metabolism
EDAT- 2006/05/13 09:00
MHDA- 2006/07/21 09:00
CRDT- 2006/05/13 09:00
PHST- 2006/05/13 09:00 [pubmed]
PHST- 2006/07/21 09:00 [medline]
PHST- 2006/05/13 09:00 [entrez]
AID - 10.1163/156856206775997287 [doi]
PST - ppublish
SO  - J Biomater Sci Polym Ed. 2006;17(3):341-55. doi: 10.1163/156856206775997287.