PMID- 16690352
OWN - NLM
STAT- MEDLINE
DCOM- 20070130
LR  - 20220408
IS  - 1388-9842 (Print)
IS  - 1388-9842 (Linking)
VI  - 8
IP  - 7
DP  - 2006 Nov
TI  - Fatigue and anaemia in patients with chronic heart failure.
PG  - 744-9
AB  - BACKGROUND: Fatigue is common in patients with chronic heart failure (CHF) and 
      has great impact on functional ability and daily activity. Although anaemia is 
      associated with fatigue, the relationship between fatigue and anaemia is unclear 
      in CHF. The aim of this study was to describe the fatigue experience and its 
      relationship to haemoglobin (Hb) concentration and to evaluate its effect on 
      health-related quality of life in an unselected hospitalised CHF population. 
      METHODS: Ninety three consecutive patients hospitalised with a diagnosis of CHF, 
      enrolled in the EuroHeart Failure Survey, completed the Multidimensional Fatigue 
      Inventory Scale (MFI-20). New York Heart Association (NYHA) functional class, 
      quality of life and haemoglobin were also assessed. RESULTS: Anaemia (Hb < or = 
      125 g/L) was found in 31 (33%) patients. The perception of fatigue differed 
      significantly between patients with CHF and healthy individuals. Anaemic patients 
      reported significantly more fatigue compared to non-anaemic patients. Decreased 
      haemoglobin and higher NYHA class explained 30% of the variance in General 
      Fatigue. Perceived fatigue was also inversely related to global health and 
      quality of life. CONCLUSION: Our findings suggest that the subjective experience 
      of fatigue in patients with CHF is associated with low haemoglobin concentration 
      and reduced functional status after controlling for age and sex.
FAU - Falk, Kristin
AU  - Falk K
AD  - Institute of Nursing, Faculty of Health and Caring Sciences, The Sahlgrenska 
      Academy at Goteborg University, Box 457, S-405 30 Goteborg, Sweden. 
      Kristin.Falk@fhs.gu.se
FAU - Swedberg, Karl
AU  - Swedberg K
FAU - Gaston-Johansson, Fannie
AU  - Gaston-Johansson F
FAU - Ekman, Inger
AU  - Ekman I
LA  - eng
PT  - Journal Article
DEP - 20060511
PL  - England
TA  - Eur J Heart Fail
JT  - European journal of heart failure
JID - 100887595
RN  - 0 (Hemoglobins)
SB  - IM
MH  - Aged
MH  - Anemia/blood/etiology/*psychology
MH  - Fatigue/blood/etiology/*psychology
MH  - Female
MH  - Gender Identity
MH  - Heart Failure/complications/*psychology
MH  - Hemoglobins/metabolism
MH  - Hospitalization
MH  - Humans
MH  - Male
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Surveys and Questionnaires
EDAT- 2006/05/13 09:00
MHDA- 2007/01/31 09:00
CRDT- 2006/05/13 09:00
PHST- 2005/06/16 00:00 [received]
PHST- 2005/11/08 00:00 [revised]
PHST- 2006/01/26 00:00 [accepted]
PHST- 2006/05/13 09:00 [pubmed]
PHST- 2007/01/31 09:00 [medline]
PHST- 2006/05/13 09:00 [entrez]
AID - S1388-9842(06)00047-X [pii]
AID - 10.1016/j.ejheart.2006.01.016 [doi]
PST - ppublish
SO  - Eur J Heart Fail. 2006 Nov;8(7):744-9. doi: 10.1016/j.ejheart.2006.01.016. Epub 
      2006 May 11.