PMID- 16702463
OWN - NLM
STAT- MEDLINE
DCOM- 20060905
LR  - 20151119
IS  - 1527-1323 (Electronic)
IS  - 0271-5333 (Linking)
VI  - 26
IP  - 3
DP  - 2006 May-Jun
TI  - From the archives of the AFIP: Pleuropulmonary synovial sarcoma.
PG  - 923-40
AB  - Pleuropulmonary synovial sarcoma (PPSS) is increasingly recognized as a subtype 
      of sarcoma because of the recent identification of a distinctive chromosomal 
      translocation specific to synovial sarcoma. Soft-tissue synovial sarcoma is far 
      more common than PPSS and typically develops in para-articular locations of the 
      extremities; affects young and middle-aged adults, with no difference in 
      distribution between the sexes; and has well-documented radiologic 
      manifestations. PPSS may arise in the chest wall, heart, mediastinum, pleura, or 
      lung, and it shares patient demographics and several imaging features with its 
      soft-tissue counterpart. Patients present with a cough, chest pain, or dyspnea. 
      On chest radiographs, PPSS typically appears as a sharply marginated mass with 
      uniform opacity, based either in the pleura or in the lung, and often accompanied 
      by an ipsilateral pleural effusion. Computed tomographic images show a 
      well-circumscribed heterogeneously enhanced lesion without associated involvement 
      of bone and without calcifications (except in the case of a chest wall primary 
      tumor). Magnetic resonance imaging provides superior demonstration of nodular 
      soft tissue and multilocular fluid-filled internal components of PPSS, in 
      addition to peripheral rim enhancement after the intravenous administration of a 
      gadolinium-based contrast material such as gadopentetate dimeglumine. Current 
      treatment consists of surgical resection followed by chemotherapy, radiation 
      therapy, or both.
FAU - Frazier, Aletta Ann
AU  - Frazier AA
AD  - Department of Radiologic Pathology, Armed Forces Institute of Pathology, 14th St 
      and Alaska Ave NW, Washington, DC 20306-6000, USA. frazier@afip.osd.mil
FAU - Franks, Teri J
AU  - Franks TJ
FAU - Pugatch, Robert D
AU  - Pugatch RD
FAU - Galvin, Jeffrey R
AU  - Galvin JR
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Radiographics
JT  - Radiographics : a review publication of the Radiological Society of North 
      America, Inc
JID - 8302501
RN  - 0 (Contrast Media)
SB  - IM
MH  - Contrast Media
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Lung Neoplasms/*diagnosis
MH  - Magnetic Resonance Imaging/*methods
MH  - Pleural Neoplasms/*diagnosis
MH  - Practice Guidelines as Topic
MH  - Practice Patterns, Physicians'
MH  - Sarcoma, Synovial/*diagnosis
RF  - 47
EDAT- 2006/05/17 09:00
MHDA- 2006/09/06 09:00
CRDT- 2006/05/17 09:00
PHST- 2006/05/17 09:00 [pubmed]
PHST- 2006/09/06 09:00 [medline]
PHST- 2006/05/17 09:00 [entrez]
AID - 26/3/923 [pii]
AID - 10.1148/rg.263055211 [doi]
PST - ppublish
SO  - Radiographics. 2006 May-Jun;26(3):923-40. doi: 10.1148/rg.263055211.