PMID- 16724712
OWN - NLM
STAT- MEDLINE
DCOM- 20060626
LR  - 20191110
IS  - 0004-0614 (Print)
IS  - 0004-0614 (Linking)
VI  - 59
IP  - 3
DP  - 2006 Apr
TI  - [Discontinuous oral ciprofloxacin for transurethral resection of the prostate. 
      Initial results].
PG  - 274-80
AB  - OBJECTIVES: To describe the rate of infectious complications using a 
      discontinuous scheme of oral ciprofloxacin in transurethral resection of the 
      prostate (TUR-P). To try to weigh the influence of clinical background, operative 
      complications and postoperative outcome on the development of such complications. 
      To compare the results to those obtained with equal methodology using antibiotics 
      in a continual scheme until the catheter removal. METHOD: A prospective open 
      study was designed including 53 consecutive patients with sterile urine and 
      without indwelling catheter subjected to TUR-P. Patients received oral 
      ciprofloxacin 500 mg (4 doses) before going to the surgical room, the night of 
      surgery, next morning of surgery and before catheter removal. Three patients were 
      excluded after incorporation (5.6%) and all the remainders completed follow up. 
      RESULTS: Fifty patients are analyzed. Fever was present in 8 patients (16%). 
      Systemic clinical infection was present in 3 patients (6%). No isolated-germ 
      postoperative bacteriuria was present. Previous urinary infection (UTI) was 
      statistically associated to systemic clinical infection (p = 0.007) and to active 
      chronic prostatitis on operative biopsy (p = 0.002). CONCLUSION: Probably 
      previous UTI antecedent made less advisable the discontinuous scheme use in 
      TUR-P, although a greater number of patients is needed to confirm these 
      statement. When these results are compared to those using antibiotics in a 
      continual scheme until catheter removal, a significant higher frequency of fever 
      is seen (p = 0.022).
FAU - Valdevenito, Juan Pablo
AU  - Valdevenito JP
AD  - Servicio de Urologia, Hospital Clinico Universidad de Chile, Santiago. 
      jpvaldevenito@redclinicauchile.cl
FAU - Valdevenito, Raul
AU  - Valdevenito R
FAU - Gomez, Alvaro
AU  - Gomez A
FAU - Russo, Moises
AU  - Russo M
LA  - spa
PT  - English Abstract
PT  - Journal Article
TT  - Ciprofloxacino oral discontinuo en reseccion transuretral de prostata. Resultados 
      iniciales.
PL  - Spain
TA  - Arch Esp Urol
JT  - Archivos espanoles de urologia
JID - 0064757
RN  - 0 (Anti-Infective Agents)
RN  - 5E8K9I0O4U (Ciprofloxacin)
SB  - IM
MH  - Administration, Oral
MH  - Anti-Infective Agents/*administration & dosage
MH  - *Antibiotic Prophylaxis
MH  - Bacterial Infections/epidemiology/*prevention & control
MH  - Ciprofloxacin/*administration & dosage
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/epidemiology/*prevention & control
MH  - Prospective Studies
MH  - *Prostatectomy
EDAT- 2006/05/27 09:00
MHDA- 2006/06/27 09:00
CRDT- 2006/05/27 09:00
PHST- 2006/05/27 09:00 [pubmed]
PHST- 2006/06/27 09:00 [medline]
PHST- 2006/05/27 09:00 [entrez]
AID - 10.4321/s0004-06142006000300008 [doi]
PST - ppublish
SO  - Arch Esp Urol. 2006 Apr;59(3):274-80. doi: 10.4321/s0004-06142006000300008.