PMID- 16730057 OWN - NLM STAT- MEDLINE DCOM- 20070719 LR - 20060719 IS - 0093-691X (Print) IS - 0093-691X (Linking) VI - 66 IP - 3 DP - 2006 Aug TI - Porcine reproductive and respiratory syndrome virus. PG - 655-62 AB - Porcine reproductive and respiratory disease (PRRS) is an economically important disease around the globe; it has been estimated to cost the swine industry in USA approximately 560 million US dollars annually. It is well established that PRRS is caused by an enveloped, single-stranded positive-sense RNA virus known as porcine reproductive and respiratory syndrome virus (PRRSV). The inability to successfully control PRRS across farms via traditional methods (e.g. vaccine and animal flow) has led to a growing interest in area-based eradication. Important to such an initiative is information on PRRSV transmission within and between herds and intervention strategies to prevent its spread. This paper will review the current literature on selected areas of PRRS known to be important to the topic of pathogen elimination, including etiology, clinical manifestations, direct and indirect routes of transmission, as well as discuss measures for disease control, prevention and eradication. FAU - Cho, Jenny G AU - Cho JG AD - Swine Disease Eradication Center, College of Veterinary Medicine University of Minnesota, USA. FAU - Dee, Scott A AU - Dee SA LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. PT - Review DEP - 20060524 PL - United States TA - Theriogenology JT - Theriogenology JID - 0421510 SB - IM MH - Animals MH - Female MH - Male MH - Porcine Reproductive and Respiratory Syndrome/*prevention & control/*transmission MH - Risk Factors MH - Swine RF - 89 EDAT- 2006/05/30 09:00 MHDA- 2007/07/20 09:00 CRDT- 2006/05/30 09:00 PHST- 2006/05/30 09:00 [pubmed] PHST- 2007/07/20 09:00 [medline] PHST- 2006/05/30 09:00 [entrez] AID - S0093-691X(06)00258-5 [pii] AID - 10.1016/j.theriogenology.2006.04.024 [doi] PST - ppublish SO - Theriogenology. 2006 Aug;66(3):655-62. doi: 10.1016/j.theriogenology.2006.04.024. Epub 2006 May 24.