PMID- 16733912
OWN - NLM
STAT- MEDLINE
DCOM- 20060721
LR  - 20221207
IS  - 1000-503X (Print)
IS  - 1000-503X (Linking)
VI  - 28
IP  - 2
DP  - 2006 Apr
TI  - [Frequencies distribution of human leukocyte antigen-B27 subtypes in healthy 
      Chinese].
PG  - 240-3
AB  - OBJECTIVE: To investigate the frequencies distribution of human leukocyte antigen 
      (HLA)-B27 subtypes in unrelated healthy Chinese. METHOD: Polymerase chain 
      reaction sequence-based typing (PCRSBT) was used to determine HLA high-resolution 
      genotypes of 825 unrelated healthy Chinese. RESULTS: A total of 25 
      HLA-B27-positive individuals and 8 HLA-B27 subtypes were detected. These subtypes 
      and their corresponding frequencies were B * 2704 (30.77%) , B * 2705 (23.08%), B 
      * 2707 (19.23%), B * 2711 (7.69%), B * 2712 (7.69%), B * 2701 (3.85%), B * 2713 
      (3.85%) and B * 2721 (3.85%). CONCLUSION: The data obtained through PCR-SBT 
      method may serve as important reference for the research of relationship between 
      HLA-B27 subtypes and some diseases such as ankylosing spondylitis.
FAU - Yang, Guang
AU  - Yang G
AD  - Department of Forensic Science, School of Medicine, Xi'an Jiaotong University, 
      Xi'an 710061, China.
FAU - Deng, Ya-jun
AU  - Deng YJ
FAU - Yan, Chun-xia
AU  - Yan CX
FAU - Wu, Dong-ying
AU  - Wu DY
FAU - Hu, Song-nian
AU  - Hu SN
FAU - Zhu, Bo-feng
AU  - Zhu BF
FAU - Li, Sheng-bin
AU  - Li SB
FAU - Zhang, Xiu-qing
AU  - Zhang XQ
FAU - Liu, Yao
AU  - Liu Y
LA  - chi
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhongguo Yi Xue Ke Xue Yuan Xue Bao
JT  - Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
JID - 8006230
RN  - 0 (HLA-B27 Antigen)
SB  - IM
MH  - Adult
MH  - Asian People/genetics
MH  - Female
MH  - *Gene Frequency
MH  - Genetic Predisposition to Disease
MH  - HLA-B27 Antigen/classification/*genetics
MH  - Humans
MH  - Male
MH  - Polymerase Chain Reaction
MH  - Sequence Analysis, DNA
MH  - Spondylitis, Ankylosing/genetics
EDAT- 2006/06/01 09:00
MHDA- 2006/07/22 09:00
CRDT- 2006/06/01 09:00
PHST- 2006/06/01 09:00 [pubmed]
PHST- 2006/07/22 09:00 [medline]
PHST- 2006/06/01 09:00 [entrez]
PST - ppublish
SO  - Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2006 Apr;28(2):240-3.