PMID- 16735038
OWN - NLM
STAT- MEDLINE
DCOM- 20090417
LR  - 20191210
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1130
IP  - 1
DP  - 2006 Oct 13
TI  - Hyphenation of infrared spectroscopy to liquid chromatography for qualitative and 
      quantitative polymer analysis: degradation of poly(bisphenol A)carbonate.
PG  - 34-42
AB  - Hyphenation of infrared spectroscopy (IR) to liquid chromatography (LC) has been 
      applied to study chemical changes in poly(bisphenol A)carbonate (PC) as a result 
      of degradation. Especially coupling of LC to FTIR through solvent elimination is 
      a sensitive approach to identify changes in functionality observed in the LC 
      chromatograms as has been demonstrated by coupling of liquid chromatography under 
      critical conditions (LCCC) to IR. Furthermore, an example is shown in which 
      two-dimensional liquid chromatography, i.e. LCCC x SEC, was coupled to IR by 
      means of a flow cell. This resulted in data sets containing most probably 
      valuable data, but extracting relevant information from these large data sets is 
      not straightforward at all. Therefore, multivariate data analysis (MVDA) of 
      SEC-FTIR data was used to extract relevant data from large data sets. This 
      approach revealed chemical differences due to degradation that could not be 
      detected by other means. Spectral features could be identified that allowed to 
      quantitatively predict the degradation of poly(bisphenol A)carbonate as a 
      function of degradation conditions.
FAU - Coulier, Leon
AU  - Coulier L
AD  - Packaging Research and Polymer Analysis Group, Analytical Sciences Department, 
      TNO Quality of Life, Utrechtseweg 48, 3704 HE Zeist, The Netherlands. 
      coulier@voeding.tno.nl
FAU - Kaal, Erwin
AU  - Kaal E
FAU - Hankemeier, Thomas
AU  - Hankemeier T
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20060602
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Benzhydryl Compounds)
RN  - 0 (Polymers)
RN  - 25037-45-0 (bisphenol-A-polycarbonate)
SB  - IM
MH  - Benzhydryl Compounds
MH  - Chromatography, Liquid/*instrumentation/*methods
MH  - Multivariate Analysis
MH  - Polymers/*analysis/*metabolism
MH  - Spectrophotometry, Infrared/*methods
EDAT- 2006/06/01 09:00
MHDA- 2009/04/18 09:00
CRDT- 2006/06/01 09:00
PHST- 2006/03/13 00:00 [received]
PHST- 2006/04/18 00:00 [revised]
PHST- 2006/04/19 00:00 [accepted]
PHST- 2006/06/01 09:00 [pubmed]
PHST- 2009/04/18 09:00 [medline]
PHST- 2006/06/01 09:00 [entrez]
AID - S0021-9673(06)00855-7 [pii]
AID - 10.1016/j.chroma.2006.04.070 [doi]
PST - ppublish
SO  - J Chromatogr A. 2006 Oct 13;1130(1):34-42. doi: 10.1016/j.chroma.2006.04.070. 
      Epub 2006 Jun 2.