PMID- 16754520
OWN - NLM
STAT- MEDLINE
DCOM- 20060627
LR  - 20231213
IS  - 0277-0903 (Print)
IS  - 0277-0903 (Linking)
VI  - 43
IP  - 3
DP  - 2006 Apr
TI  - Allergic memory of patients sensitized to castor bean after a long 
      stimulation-free period.
PG  - 193-8
AB  - We have taken advantage of the temporary exposure of Marseilles population to 
      castor bean seed proteins to follow 26 allergic patients more than 20 years after 
      sensitization. Skin tests, specific immunoglobulin E (IgE) antibody assays, and 
      specific immunoblots were performed. Skin test reactivity to Ricinus Communis and 
      specific IgE concentrations decreased progressively and almost completely 
      disappeared after 20 years. Specific IgE concentration displayed a fairly 
      exponential decrease, with a half-life of 4.7 years. Thus, in the absence of any 
      antigenic stimulation, directly by castor bean, or indirectly by cross-reactivity 
      to other Euphorbiaceae, especially latex, IgE sensitization is bound to 
      disappear.
FAU - Marin, Valerie
AU  - Marin V
AD  - Laboratoire d'immunologie, Universite de la Mediterranee, Hopital de Sainte 
      Marguerite, Marseille, France. valerie.marin@ap-hm.fr
FAU - Saraga, Jacques
AU  - Saraga J
FAU - Ariano, Renato
AU  - Ariano R
FAU - Chouquet, Didier
AU  - Chouquet D
FAU - Dispard, Melanie
AU  - Dispard M
FAU - Bongrand, Pierre
AU  - Bongrand P
FAU - Panzani, Raphael C
AU  - Panzani RC
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Asthma
JT  - The Journal of asthma : official journal of the Association for the Care of 
      Asthma
JID - 8106454
RN  - 0 (Air Pollutants)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Air Pollutants/*immunology
MH  - Ricinus communis/*immunology
MH  - Cohort Studies
MH  - Female
MH  - France
MH  - Humans
MH  - Immunoblotting
MH  - Immunoglobulin E/*immunology
MH  - *Immunologic Memory
MH  - Male
MH  - Middle Aged
MH  - Respiratory Hypersensitivity/*immunology
MH  - Seeds
MH  - Skin Tests
EDAT- 2006/06/07 09:00
MHDA- 2006/06/28 09:00
CRDT- 2006/06/07 09:00
PHST- 2006/06/07 09:00 [pubmed]
PHST- 2006/06/28 09:00 [medline]
PHST- 2006/06/07 09:00 [entrez]
AID - M607883N07H67744 [pii]
AID - 10.1080/02770900600566686 [doi]
PST - ppublish
SO  - J Asthma. 2006 Apr;43(3):193-8. doi: 10.1080/02770900600566686.