PMID- 16777399
OWN - NLM
STAT- MEDLINE
DCOM- 20060919
LR  - 20240227
IS  - 0952-7915 (Print)
IS  - 0952-7915 (Linking)
VI  - 18
IP  - 4
DP  - 2006 Aug
TI  - T cell-dendritic cell immunological synapses.
PG  - 512-6
AB  - Dendritic cells (DCs) are myeloid lineage cells that are imprinted by their 
      environment and that mature in response to microbial products. A crucial role of 
      the DC is to impart this context-specific information to T cells as well as to 
      present self and foreign MHC-peptide complexes through formation of an 
      immunological synapse. The structure of the T cell-DC immunological synapse 
      departs from the canonical structure formed with B cells or with supported planar 
      bilayers in that it has multiple foci of T-cell receptor interactions rather than 
      a central focus. Recent studies on model systems provide insight into the 
      mechanisms and biological consequences of the unique T cell-DC synaptic patterns.
FAU - Dustin, Michael L
AU  - Dustin ML
AD  - Program in Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine 
      and Department of Pathology, New York University School of Medicine, NY 10016, 
      USA.
FAU - Tseng, Su-Yi
AU  - Tseng SY
FAU - Varma, Rajat
AU  - Varma R
FAU - Campi, Gabriele
AU  - Campi G
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20060613
PL  - England
TA  - Curr Opin Immunol
JT  - Current opinion in immunology
JID - 8900118
RN  - 0 (Lipid Bilayers)
SB  - IM
MH  - Animals
MH  - Cell Communication/*immunology
MH  - Cell Membrane/immunology
MH  - Dendritic Cells/cytology/*immunology
MH  - Humans
MH  - Lipid Bilayers/immunology
MH  - T-Lymphocytes/cytology/*immunology
RF  - 32
EDAT- 2006/06/17 09:00
MHDA- 2006/09/20 09:00
CRDT- 2006/06/17 09:00
PHST- 2006/04/13 00:00 [received]
PHST- 2006/05/31 00:00 [accepted]
PHST- 2006/06/17 09:00 [pubmed]
PHST- 2006/09/20 09:00 [medline]
PHST- 2006/06/17 09:00 [entrez]
AID - S0952-7915(06)00110-5 [pii]
AID - 10.1016/j.coi.2006.05.017 [doi]
PST - ppublish
SO  - Curr Opin Immunol. 2006 Aug;18(4):512-6. doi: 10.1016/j.coi.2006.05.017. Epub 
      2006 Jun 13.